The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

The acute respiratory distress syndrome (ARDS) is an important cause of acute respiratory
failure that is often associated with multiple organ failure. Several clinical disorders can …

The acute respiratory distress syndrome is a common, devastating clinical syndrome of
acute lung injury that affects both medical and surgical patients. Since the last review of this …

Recent studies have suggested that bone marrow-derived multipotent mesenchymal stem
cells (MSCs) may have therapeutic applications in multiple clinical disorders including …

Morbidity and mortality have declined only modestly in patients with clinical acute lung injury
(ALI) and acute respiratory distress syndrome (ARDS), despite extensive research into the …

Considerable progress has been made in understanding the basic mechanisms that
regulate fluid and protein exchange across the endothelial and epithelial barriers of the lung …

Abstract The epithelial Na+ channel (ENaC) transports Na+ across tight epithelia, including
the distal nephron. Different paradigms of ENaC regulation include extrinsic and intrinsic …

Sodium absorption by an amiloride-sensitive channel is the main driving force of lung liquid
clearance at birth and lung edema clearance in adulthood. In this study, we tested whether …

The epithelial Na+ channel (ENaC) is a tetramer of two α-, one β-, and one γ-subunit, but
little is known about its assembly and processing. Because co-expression of mouse ENaC …

The study of human monogenic diseases [pseudohypoaldosteronism type 1 (PHA-1) and
Liddle's syndrome] as well as mouse models mimicking the salt-losing syndrome (PHA-1) or …