Opening doors with ultrasound and microbubbles: Beating biological barriers to promote drug delivery
Apart from its clinical use in imaging, ultrasound has been thoroughly investigated as a tool
to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such …
to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such …
Functional roles of astrocyte calcium elevations: from synapses to behavior
Astrocytes are fundamental players in the regulation of synaptic transmission and plasticity.
They display unique morphological and phenotypical features that allow to monitor and to …
They display unique morphological and phenotypical features that allow to monitor and to …
Brain tumour cells interconnect to a functional and resistant network
Astrocytic brain tumours, including glioblastomas, are incurable neoplasms characterized by
diffusely infiltrative growth. Here we show that many tumour cells in astrocytomas extend …
diffusely infiltrative growth. Here we show that many tumour cells in astrocytomas extend …
[图书][B] Stochastic processes in cell biology
PC Bressloff - 2014 - Springer
One of the major challenges in modern biology is to understand how the molecular
components of a living cell operate in a highly noisy environment. What are the specific …
components of a living cell operate in a highly noisy environment. What are the specific …
Structure and function of IP3 receptors
Inositol 1, 4, 5-trisphosphate receptors (IP3Rs), by releasing Ca2+ from the endoplasmic
reticulum (ER) of animal cells, allow Ca2+ to be redistributed from the ER to the cytosol or …
reticulum (ER) of animal cells, allow Ca2+ to be redistributed from the ER to the cytosol or …
[HTML][HTML] The many faces of calmodulin in cell proliferation, programmed cell death, autophagy, and cancer
MW Berchtold, A Villalobo - Biochimica et Biophysica Acta (BBA)-Molecular …, 2014 - Elsevier
Calmodulin (CaM) is a ubiquitous Ca 2+ receptor protein mediating a large number of
signaling processes in all eukaryotic cells. CaM plays a central role in regulating a myriad of …
signaling processes in all eukaryotic cells. CaM plays a central role in regulating a myriad of …
Connexins in the heart: regulation, function and involvement in cardiac disease
A Rodríguez-Sinovas, JA Sánchez… - International journal of …, 2021 - mdpi.com
Connexins are a family of transmembrane proteins that play a key role in cardiac physiology.
Gap junctional channels put into contact the cytoplasms of connected cardiomyocytes …
Gap junctional channels put into contact the cytoplasms of connected cardiomyocytes …
A complete biomechanical model of Hydra contractile behaviors, from neural drive to muscle to movement
H Wang, J Swore, S Sharma… - Proceedings of the …, 2023 - National Acad Sciences
How does neural activity drive muscles to produce behavior? The recent development of
genetic lines in Hydra that allow complete calcium imaging of both neuronal and muscle …
genetic lines in Hydra that allow complete calcium imaging of both neuronal and muscle …
Macrophage-derived netrin-1 promotes abdominal aortic aneurysm formation by activating MMP3 in vascular smooth muscle cells
T Hadi, L Boytard, M Silvestro, D Alebrahim… - Nature …, 2018 - nature.com
Abdominal aortic aneurysms (AAA) are characterized by extensive extracellular matrix
(ECM) fragmentation and inflammation. However, the mechanisms by which these events …
(ECM) fragmentation and inflammation. However, the mechanisms by which these events …
A bioelectrical phase transition patterns the first vertebrate heartbeats
A regular heartbeat is essential to vertebrate life. In the mature heart, this function is driven
by an anatomically localized pacemaker. By contrast, pacemaking capability is broadly …
by an anatomically localized pacemaker. By contrast, pacemaking capability is broadly …