The hybridization of heterocycles presents a key opportunity to craft innovative multicyclic
compounds with enhanced biological activity. Coumarins, being broadly prevalent natural …

Sweet bell pepper (SBP, Capsicum annuum L.) can be employed as a spice in many dishes
and may also be eaten as a delicious fruit. These two nutritional attributes are owing to the …

Fluorouracil (5-FU) has been commonly used as a chemotherapy medication in cancer
management. However, owing to its substantial side effects, limited selectivity, and tumor …

Abstract 3, 4, 5-Trimethoxy-3′-hydroxy-4′-methoxystilbene (TMHMS) is an anticancer
natural stilbene that targets tubulin polymerization. According to research, oxidative stress …

A potent natural combretastatin, combretastatin A-4 (COMA4) targets the condylon active
pocket to produce anticancer effects. Studies on inflammation and oxidative stress have …

Phyto-coumarins demonstrate diverse biological actions, encompassing antiradical, anti-
inflammatory, oncolytic, monoamine oxidase B (MAOB) suppression, and antibacterial …

In this work, two chlorophenols with particular toxicities were transformed into their 14
corresponding coumarins (CMs). Their chemical structures were confirmed by examining the …

This study presents, for the first time, the synthesis of innovative conjugates identified as a
five-membered ring integrating three heteroatoms linked linearly to the coumarin framework …

Phytocoumarins exhibit a range of biological activities, including antibacterial, anti-
inflammatory, antiradical, oncolytic, and reduction of monoamine oxidase B effects. These …

With the widespread use of pesticides, environmental pollution has elevated to a top priority
for humans. The pentachlorophenol (PCP) is one of the most dangerous chlorophenols …