Numerous studies have shown that non–cell-autonomous regulation of cancer cells is an
important aspect of tumorigenesis. Cancer cells need to communicate with stromal cells by …

The glutathione (GSH) content of cancer cells is particularly relevant in regulating mutagenic
mechanisms, DNA synthesis, growth, and multidrug and radiation resistance. In malignant …

Brain metastasis is an important cause of mortality in breast cancer patients. A key event
during brain metastasis is the migration of cancer cells through blood–brain barrier (BBB) …

Anionic phospholipids are largely absent from the external leaflet of the plasma membrane
of mammalian cells under normal conditions. Exposure of phosphatidylserine on the cell …

Blood vessels perfuse all tissues in the body and mediate vital metabolic exchange between
tissues and blood. Increasing evidence, however, points to a direct role for paracrine …

Metastasis, the process by which cancer cells leave the primary tumour, disseminate and
form secondary tumours at anatomically distant sites, is a serious clinical problem as it is …

Angiogenesis is the development of blood vessels from an existing vasculature. This
process is fundamental to both physiological wound healing and the growth of malignant …

The relationship between resveratrol (RES) bioavalability and its effect on tumor growth was
investigated. Tissue levels of RES were studied after iv and oral administration of trans …

Aquaporin (AQP) water channels are expressed in high‐grade tumor cells of different tissue
origins. Based on the involvement of AQPs in angiogenesis and cell migration, we tested …

MUC1 is a transmembrane mucin that is often overexpressed in metastatic cancers and
often used as a diagnostic marker for metastatic progression. The extracellular domain of …