Unmet medical needs in chronic, non-communicable inflammatory skin diseases

H Ujiie, D Rosmarin, MP Schön, S Ständer… - Frontiers in …, 2022 - frontiersin.org
An estimated 20–25% of the population is affected by chronic, non-communicable
inflammatory skin diseases. Chronic skin inflammation has many causes. Among the most …

Autoimmunity against laminin 332

S Patzelt, E Schmidt - Frontiers in Immunology, 2023 - frontiersin.org
Laminin 332 is a heterotrimeric structural protein of the basal membrane zone (BMZ) of the
skin and adjacent mucosal tissues. The importance of laminin 332 for the structural integrity …

S2k guidelines on the management of paraneoplastic pemphigus/paraneoplastic autoimmune multiorgan syndrome initiated by the European Academy of …

E Antiga, R Bech, R Maglie, G Genovese… - Journal of the …, 2023 - Wiley Online Library
Background Paraneoplastic pemphigus (PNP), also called paraneoplastic autoimmune
multiorgan syndrome (PAMS), is a rare autoimmune disease with mucocutaneous and multi …

Autoimmune bullous dermatoses

MM Holtsche, K Boch, E Schmidt - JDDG: Journal der …, 2023 - Wiley Online Library
Autoimmune bullous dermatoses (AIBD) are a heterogeneous group of about a dozen
diseases characterized clinically by erosions and blisters and immunopathologically by …

Pemphigus‐und Pemphigoid‐Erkrankungen: Klinik, Diagnostik und Therapie: Pemphigus and pemphigoids: Clinical presentation, diagnosis and therapy

D Didona, MF Schmidt, R Maglie… - JDDG: Journal der …, 2023 - Wiley Online Library
Pemphigus und Pemphigoid sind seltene Autoimmunkrankheiten der Haut mit potenziell
lebensbedrohlichem Verlauf. Autoantikörper gegen epidermale und junktionale …

Gut dysbiosis in ocular mucous membrane pemphigoid

L Low, K Suleiman, M Shamdas… - Frontiers in cellular …, 2022 - frontiersin.org
Mucous Membrane Pemphigoid is an orphan multi-system autoimmune scarring disease
involving mucosal sites, including the ocular surface (OcMMP) and gut. Loss of tolerance to …

Anti-laminin 332-type mucous membrane pemphigoid

L Shi, X Li, H Qian - Biomolecules, 2022 - mdpi.com
Anti-laminin (LM) 332-type mucous membrane pemphigoid (MMP) is a rare autoimmune
bullous disease and was originally discovered as anti-epiligrin cicatricial pemphigoid. Anti …

Immunoglobulin disorders and the oral cavity: a narrative review

M Ptasiewicz, D Bębnowska, P Małkowska… - Journal of Clinical …, 2022 - mdpi.com
The oral mucosa is a mechanical barrier against the penetration and colonization of
microorganisms. Oral homeostasis is maintained by congenital and adaptive systems in …

Computer-aided classification of indirect immunofluorescence patterns on esophagus and split skin for the detection of autoimmune dermatoses

J Hocke, J Krauth, C Krause, S Gerlach… - Frontiers in …, 2023 - frontiersin.org
Autoimmune bullous dermatoses (AIBD) are rare diseases that affect human skin and
mucous membranes. Clinically, they are characterized by blister formation and/or erosions …

Comparison of two diagnostic assays for anti-laminin 332 mucous membrane pemphigoid

S Goletz, F Giurdanella, MM Holtsche… - Frontiers in …, 2021 - frontiersin.org
Anti-laminin 332 mucous membrane pemphigoid (MMP) is an autoimmune blistering
disease characterized by predominant mucosal lesions and autoantibodies against laminin …