Current concepts of psoriasis immunopathogenesis
Psoriasis is a recurrent, chronic, immune-mediated, systemic inflammatory disease of the
skin, joints, and other organic systems. After atopic dermatitis, chronic stationary psoriasis is …
skin, joints, and other organic systems. After atopic dermatitis, chronic stationary psoriasis is …
Adaptive and innate immunity in psoriasis and other inflammatory disorders
MP Schön - Frontiers in immunology, 2019 - frontiersin.org
Over the past three decades, a considerable body of evidence has highlighted T cells as
pivotal culprits in the pathogenesis of psoriasis. This includes the association of psoriasis …
pivotal culprits in the pathogenesis of psoriasis. This includes the association of psoriasis …
Uncovering the cells and circuits of touch in normal and pathological settings
The sense of touch is fundamental as it provides vital, moment-to-moment information about
the nature of our physical environment. Primary sensory neurons provide the basis for this …
the nature of our physical environment. Primary sensory neurons provide the basis for this …
Dendritic cells: The driver of psoriasis
AO Wang, YP Bai - The Journal of dermatology, 2020 - Wiley Online Library
Psoriasis is a chronic skin inflammatory disorder, the immune mechanism of which has been
profoundly elucidated in the past few years. The dominance of the interleukin (IL)‐23/IL‐17 …
profoundly elucidated in the past few years. The dominance of the interleukin (IL)‐23/IL‐17 …
Psoriasis and microbiota: a systematic review
Background: Recent advances have highlighted the crucial role of microbiota in the
pathophysiology of chronic inflammatory diseases as well as its impact on the efficacy of …
pathophysiology of chronic inflammatory diseases as well as its impact on the efficacy of …
[HTML][HTML] High-fat diet exacerbates early psoriatic skin inflammation independent of obesity: saturated fatty acids as key players
D Herbert, S Franz, Y Popkova, U Anderegg… - Journal of Investigative …, 2018 - Elsevier
In obesity, hypertrophic adipocytes secrete high amounts of adipocytokines, resulting in low-
grade inflammation amplified by infiltrating proinflammatory macrophages, oxidative stress …
grade inflammation amplified by infiltrating proinflammatory macrophages, oxidative stress …
[PDF][PDF] Systemic immune-inflammation index (SII) predicts increased severity in psoriasis and psoriatic arthritis
A Yorulmaz, Y Hayran, U Akpinar, B Yalcin - Curr Health Sci J, 2020 - chsjournal.org
Background: Psoriasis is a common chronic inflammatory dermatosis. Systemic immune
inflammation index (SII) is an inflammation-based biomarker, which has been shown to be …
inflammation index (SII) is an inflammation-based biomarker, which has been shown to be …
Bioengineered skin organoids: from development to applications
ZX Hong, ST Zhu, H Li, JZ Luo, Y Yang, Y An… - Military Medical …, 2023 - Springer
Significant advancements have been made in recent years in the development of highly
sophisticated skin organoids. Serving as three-dimensional models that mimic human skin …
sophisticated skin organoids. Serving as three-dimensional models that mimic human skin …
Comorbidity in adult psoriasis: considerations for the clinician
Psoriasis is associated with several comorbidities ranging from cardiovascular comorbidity
and mental disorders to other immune mediated inflammatory diseases. However, most of …
and mental disorders to other immune mediated inflammatory diseases. However, most of …
[HTML][HTML] The role of gut microbiome in the pathogenesis of psoriasis and the therapeutic effects of probiotics
DI Alesa, HM Alshamrani, YA Alzahrani… - Journal of family …, 2019 - journals.lww.com
The adult intestine hosts a huge number of diverse bacterial species, collectively referred to
as the microbiome, that reside mainly in the lower gut, where they maintain a symbiotic …
as the microbiome, that reside mainly in the lower gut, where they maintain a symbiotic …