Solid dispersion is the preferred technology to prepare efficacious forms of BCS class-II/IV
APIs. To prepare solid dispersions, there exist a wide variety of polymeric carriers with …

Abstract We, the Editors and Publisher of Drug Delivery have retracted the following article:
Sultan Alshehri, Syed Sarim Imam, Afzal Hussain, Mohammad A. Altamimi, Nabil K …

The poor aqueous solubility of many active pharmaceutical ingredients (APIs) dominates
much of the early drug development portfolio and poses a major challenge in …

Introduction Most new drug candidates under development are poorly water-soluble, which
are related to multiple pharmaceutical issues, increasing the bioavailability of these drugs by …

Hot-melt extrusion (HME) has emerged as a pioneering manufacturing technology for
pharmaceutical industries, and the utilization is overgrowing due to its unit operation, cost …

In vitro dissolution that predicts the in vivo performance of solid preparations is extremely
important in formulation optimization. Fraction absorbed (F a) has been used to screen in …

We have previously developed a fast screening method on the ability of twenty amino acids
(AA) to form co-amorphous formulations with six drugs upon ball milling. In this work, the …

Binary co-amorphous systems (CAMS) are a type of solid dispersion containing an active
pharmaceutical ingredient (API) and small molecule excipients. The properties of these …

In this investigation, the fabrication of capsaicin loaded self nano emulsifying drug delivery
system (SNEDDS) was attempted to improve the effectiveness of capsaicin through the oral …

New drugs are frequently found with poor water-solubility in recent pharmaceutical projects,
which brings difficulties of bioavailability for the clinical development of new drugs. When …