Pathogenesis, multi-omics research, and clinical treatment of psoriasis
J Yu, Q Zhao, X Wang, H Zhou, J Hu, L Gu, Y Hu… - Journal of …, 2022 - Elsevier
Psoriasis is a common inflammatory skin disease involving interactions between
keratinocytes and immune cells that significantly affects the quality of life. It is characterized …
keratinocytes and immune cells that significantly affects the quality of life. It is characterized …
Signaling pathways and targeted therapies for psoriasis
J Guo, H Zhang, W Lin, L Lu, J Su… - Signal Transduction and …, 2023 - nature.com
Psoriasis is a common, chronic, and inflammatory skin disease with a high burden on
individuals, health systems, and society worldwide. With the immunological pathologies and …
individuals, health systems, and society worldwide. With the immunological pathologies and …
Vulvar lichen sclerosus from pathophysiology to therapeutic approaches: evidence and prospects
M Corazza, N Schettini, P Zedde, A Borghi - Biomedicines, 2021 - mdpi.com
Vulvar lichen sclerosus (VLS) is a chronic, distressing, inflammatory disease with an
enormous impact on quality of life. Treatment goals are relieving symptoms, reversing signs …
enormous impact on quality of life. Treatment goals are relieving symptoms, reversing signs …
Research progress of single-cell transcriptome sequencing in autoimmune diseases and autoinflammatory disease: A review
L Zeng, K Yang, T Zhang, X Zhu, W Hao, H Chen… - Journal of …, 2022 - Elsevier
Autoimmunity refers to the phenomenon that the body's immune system produces antibodies
or sensitized lymphocytes to its own tissues to cause an immune response. Immune …
or sensitized lymphocytes to its own tissues to cause an immune response. Immune …
Immune cells in the epithelial immune microenvironment of psoriasis: emerging therapeutic targets
L Li, J Lu, J Liu, J Wu, X Zhang, Y Meng, X Wu… - Frontiers in …, 2024 - frontiersin.org
Psoriasis is a chronic autoimmune inflammatory disease characterized by erroneous
metabolism of keratinocytes. The development of psoriasis is closely related to abnormal …
metabolism of keratinocytes. The development of psoriasis is closely related to abnormal …
Potential biomarkers for psoriasis topical treatment by in-depth serum proteomics
J Cui, X Zhang, J Deng, Y Yan, D Yao… - Journal of …, 2023 - Taylor & Francis
Background Psoriasis is a chronic skin disease, and topical sequential therapy with a
combination of calcipotriol and calcipotriol betamethasone is currently approved topical …
combination of calcipotriol and calcipotriol betamethasone is currently approved topical …
AIM2 and psoriasis
Y Zhang, X Xu, H Cheng, F Zhou - Frontiers in Immunology, 2023 - frontiersin.org
Psoriasis is a chronic inflammatory skin disease occurring worldwide, with multiple systemic
complications, which seriously affect the quality of life and physical and mental health of …
complications, which seriously affect the quality of life and physical and mental health of …
MicroRNA profiling of psoriatic skin identifies 11 miRNAs associated with disease severity
ÅØ Solvin, K Chawla, LC Olsen… - Experimental …, 2022 - Wiley Online Library
MicroRNAs (miRNAs) are small non‐coding RNAs that have emerged as central regulators
of gene expression and powerful biomarkers of disease. Much is yet unknown about their …
of gene expression and powerful biomarkers of disease. Much is yet unknown about their …
Drug delivery through the psoriatic epidermal barrier—A “skin-on-a-chip” permeability study and ex vivo optical imaging
Psoriasis is a chronic inflammatory disease with unmet medical needs. To clarify potential
therapeutic targets, different animal models have been developed. In the current study …
therapeutic targets, different animal models have been developed. In the current study …
The involvement of cysteine-X-cysteine motif chemokine receptors in skin homeostasis and the pathogenesis of allergic contact dermatitis and psoriasis
W Liu - International Journal of Molecular Sciences, 2024 - mdpi.com
Members of the CXC motif chemokine receptor (CXCR) superfamily play central roles in
initiating the innate immune response in mammalian cells by orchestrating selective cell …
initiating the innate immune response in mammalian cells by orchestrating selective cell …