[HTML][HTML] The p53 family member p73 in the regulation of cell stress response

JM Rozenberg, S Zvereva, A Dalina, I Blatov, I Zubarev… - Biology direct, 2021 - Springer
During oncogenesis, cells become unrestrictedly proliferative thereby altering the tissue
homeostasis and resulting in subsequent hyperplasia. This process is paralleled by …

[HTML][HTML] The effects of mutant Ras proteins on the cell signalome

T Takács, G Kudlik, A Kurilla, B Szeder, L Buday… - Cancer and Metastasis …, 2020 - Springer
The genetic alterations in cancer cells are tightly linked to signaling pathway dysregulation.
Ras is a key molecule that controls several tumorigenesis-related processes, and mutations …

Targeting KRAS in pancreatic cancer: Emerging therapeutic strategies

S Khan, V Budamagunta, D Zhou - Advances in Cancer Research, 2023 - Elsevier
KRAS, a predominant member of the RAS family, is the most frequently mutated oncogene
in human pancreatic cancer (∼ 95% of cases). Mutations in KRAS lead to its constitutive …

[HTML][HTML] Protein kinase C (PKC) isozymes as diagnostic and prognostic biomarkers and therapeutic targets for cancer

T Kawano, J Inokuchi, M Eto, M Murata, JH Kang - Cancers, 2022 - mdpi.com
Simple Summary Protein kinase C (PKC) isozymes play key roles in the proliferation,
differentiation, survival, migration, invasion, apoptosis, and anticancer drug resistance of …

[HTML][HTML] Baicalin inhibits human cervical cancer cells by suppressing protein kinase C/signal transducer and activator of transcription (PKC/STAT3) signaling pathway

Q Wang, H Xu, X Zhao - Medical science monitor: international …, 2018 - ncbi.nlm.nih.gov
Background Like other human cancers, the malignancy of cervical cancer is also
characterized by abilities of proliferation, migration, and invasion. Protein kinase C-zeta …

Hypothalamic extended synaptotagmin-3 contributes to the development of dietary obesity and related metabolic disorders

Y Zhang, Y Guan, S Pan, L Yan… - Proceedings of the …, 2020 - National Acad Sciences
The C2 domain containing protein extended synaptotagmin (E-Syt) plays important roles in
both lipid homeostasis and the intracellular signaling; however, its role in physiology …

[PDF][PDF] Protein Kinase C (PKC) Isozymes as Diagnostic and Prognostic Biomarkers and Therapeutic Targets for Cancer. Cancers 2022, 14, 5425

T Kawano, J Inokuchi, M Eto, M Murata, JH Kang - 2022 - pdfs.semanticscholar.org
Protein kinase C (PKC) is a large family of calcium-and phospholipid-dependent
serine/threonine kinases that consists of at least 11 isozymes. Based on their structural …

Genetic analyses of differences between solid and nonsolid predominant lung adenocarcinomas

J Luo, K Ma, Y Shi, Z Chen, M Zhao, Y Huang… - Thoracic …, 2018 - Wiley Online Library
Background Solid predominant lung adenocarcinomas (LUAD) have distinct
histopathological and clinical characteristics compared with nonsolid subtypes. A …