Recent Insights into Particulate Matter (PM2.5)-Mediated Toxicity in Humans: An Overview

P Thangavel, D Park, YC Lee - International journal of environmental …, 2022 - mdpi.com
Several epidemiologic and toxicological studies have commonly viewed ambient fine
particulate matter (PM2. 5), defined as particles having an aerodynamic diameter of less …

Molecular mechanisms of environmental exposures and human disease

H Wu, CM Eckhardt, AA Baccarelli - Nature reviews genetics, 2023 - nature.com
A substantial proportion of disease risk for common complex disorders is attributable to
environmental exposures and pollutants. An appreciation of how environmental pollutants …

Nrf2 regulates oxidative stress and its role in cerebral ischemic stroke

L Wang, X Zhang, X Xiong, H Zhu, R Chen, S Zhang… - Antioxidants, 2022 - mdpi.com
Cerebral ischemic stroke is characterized by acute ischemia in a certain part of the brain,
which leads to brain cells necrosis, apoptosis, ferroptosis, pyroptosis, etc. At present, there …

[HTML][HTML] Role of air pollutants in airway epithelial barrier dysfunction in asthma and COPD

M Aghapour, ND Ubags, D Bruder… - European …, 2022 - Eur Respiratory Soc
Chronic exposure to environmental pollutants is a major contributor to the development and
progression of obstructive airway diseases, including asthma and COPD. Understanding the …

[HTML][HTML] Protective actions of nuclear factor erythroid 2-related factor 2 (NRF2) and downstream pathways against environmental stressors

MTB Jimenez, K Frenis, O Hahad, S Steven… - Free Radical Biology …, 2022 - Elsevier
Environmental risk factors, including noise, air pollution, chemical agents, ultraviolet
radiation (UVR) and mental stress have a considerable impact on human health. Oxidative …

Mitigating oil and gas pollutants for a sustainable environment–Critical review and prospects

A Haruna, G Tanimu, I Ibrahim, ZN Garba… - Journal of Cleaner …, 2023 - Elsevier
The oil and gas (O&G) industry generate pollutants from the exploration, refining,
transportation, storage, and consumption of crude oil products that potentially pollute soil …

Analytical chemistry, formation, mitigation, and risk assessment of polycyclic aromatic hydrocarbons: From food processing to in vivo metabolic transformation

Y Zhang, X Chen, Y Zhang - … in Food Science and Food Safety, 2021 - Wiley Online Library
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous in the air, oils, water, and food
products we encounter every day. Among these exposures, food consumption is a major …

Superoxide release by macrophages through NADPH oxidase activation dominating chemistry by isoprene secondary organic aerosols and quinones to cause …

T Fang, YK Huang, J Wei… - … science & technology, 2022 - ACS Publications
Oxidative stress mediated by reactive oxygen species (ROS) is a key process for adverse
aerosol health effects. Secondary organic aerosols (SOA) account for a major fraction of fine …

Redox and inflammatory mechanisms linking air pollution particulate matter with cardiometabolic derangements

T Marchini - Free Radical Biology and Medicine, 2023 - Elsevier
Air pollution is the largest environmental risk factor for disease and premature death. Among
the different components that are present in polluted air, fine particulate matter below 2.5 μm …

Accelerated vascular aging in chronic kidney disease: the potential for novel therapies

S Hobson, S Arefin, A Witasp, L Hernandez… - Circulation …, 2023 - Am Heart Assoc
The pathophysiology of vascular disease is linked to accelerated biological aging and a
combination of genetic, lifestyle, biological, and environmental risk factors. Within the …