Adaptive immune responses mediated by T cells and B cells are crucial for protective
immunity against pathogens and tumors. Differentiation and function of immune cells require …

Productive T cell responses to infection and cancer rely on coordinated metabolic
reprogramming and epigenetic remodeling among the immune cells. In particular, T cell …

Both T-cell deprivation and insufficient tumor immunogenicity seriously hinder the efficacy of
immune-mediated tumor destruction in melanoma. In this work, an amphiphilic polyethylene …

Metabolic adaptation to viral infections critically determines the course and manifestations of
disease. At the systemic level, a significant feature of viral infection and inflammation that …

Colorectal cancer (CRC) is the third most common cancer and the second leading cause of
cancer-related death worldwide. Countless CRC patients undergo disease progression. As …

The alternations in the hypoxic and immune microenvironment are closely related to the
therapeutic effect and prognosis of oral squamous cell carcinoma (OSCC). Herein, a new …

Virus-specific CD8+ T cells that differentiate in the context of resolved versus persisting
infections exhibit divergent phenotypic and functional characteristics, which suggests that …

Activation of the cyclic GMP‐AMP synthase‐stimulator of the interferon gene (cGAS‐STING)
pathway is a potent anticancer immunotherapeutic strategy, and the induction of pyroptosis …

CD8+ T cell longevity regulated by metabolic activity plays important roles in cancer
immunotherapy. Although in vitro–polarized, transferred IL-9–secreting CD8+ Tc9 (cytotoxic …

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …