ErbB receptors and cancer

Z Wang - ErbB receptor signaling: methods and protocols, 2017 - Springer
The ErbB receptor family, also known as the EGF receptor family or type I receptor family,
includes the epidermal growth factor (EGF) receptor (EGFR) or ErbB1/Her1, ErbB2/Her2 …

Oral complications of targeted cancer therapies: a narrative literature review

AL Watters, JB Epstein, M Agulnik - Oral oncology, 2011 - Elsevier
The aim of the present study was to investigate the available literature regarding the oral
side effects or adverse events associated with targeted cancer therapy. Common oral …

Bevacizumab plus erlotinib in Chinese patients with untreated, EGFR-mutated, advanced NSCLC (ARTEMIS-CTONG1509): a multicenter phase 3 study

Q Zhou, CR Xu, Y Cheng, YP Liu, GY Chen, JW Cui… - Cancer cell, 2021 - cell.com
Dual inhibition of epidermal growth factor receptor (EGFR) and vascular endothelial growth
factor (VEGF) pathways may delay therapeutic resistance in advanced non-small cell lung …

Napsin A and thyroid transcription factor-1 expression in carcinomas of the lung, breast, pancreas, colon, kidney, thyroid, and malignant mesothelioma

JA Bishop, R Sharma, PB Illei - Human pathology, 2010 - Elsevier
Recent advances in the treatment of pulmonary adenocarcinoma have increased the need
for accurate typing of non–small cell carcinomas. Immunohistochemistry for thyroid …

Combinatorial Action of MicroRNAs let-7 and miR-34 Effectively Synergizes with Erlotinib to Suppress Non-small Cell Lung Cancer Cell Proliferation

C Stahlhut, FJ Slack - Cell cycle, 2015 - Taylor & Francis
Lung cancer represents the leading cause of cancer-related deaths in men and women
worldwide. Targeted therapeutics, including the epidermal growth factor receptor (EGFR) …

Unleashing the power of inhibitors of oncogenic kinases through BH3 mimetics

MS Cragg, C Harris, A Strasser, CL Scott - Nature Reviews Cancer, 2009 - nature.com
Therapeutic targeting of tumours on the basis of molecular analysis is a new paradigm for
cancer treatment but has yet to fulfil expectations. For many solid tumours, targeted …

[HTML][HTML] Recent advances in anti-angiogenic therapy of cancer

RS Samant, LA Shevde - Oncotarget, 2011 - ncbi.nlm.nih.gov
Since angiogenesis is critical for tumor growth and metastasis, anti-angiogenic treatment is
a highly promising therapeutic approach. Thus, for over last couple of decades, there has …

[HTML][HTML] Bevacizumab counteracts VEGF-dependent resistance to erlotinib in an EGFR-mutated NSCLC xenograft model

C Masuda, M Yanagisawa… - International …, 2017 - spandidos-publications.com
Erlotinib, an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), shows
superior efficacy in patients with non-small cell lung cancer (NSCLC) harboring activating …

[HTML][HTML] Should progression-free survival be the primary measure of efficacy for advanced NSCLC therapy?

JC Soria, C Massard, T Le Chevalier - Annals of Oncology, 2010 - Elsevier
Non-small-cell lung cancer (NSCLC) is a leading cause of malignancy-related mortality in
the Western world. Despite advances in early detection and standard treatment, NSCLC is …

Peptide G-protein-coupled receptors and ErbB receptor tyrosine kinases in cancer

TW Moody, I Ramos-Alvarez, RT Jensen - Biology, 2023 - mdpi.com
Simple Summary Cancer growth is regulated by receptor tyrosine kinases (RTKs) and G-
protein-coupled receptors (GPCRs). The epidermal growth factor receptor (EGFR) is an RTK …