Biological response of cancer cells to radiation treatment

R Baskar, J Dai, N Wenlong, R Yeo… - Frontiers in molecular …, 2014 - frontiersin.org
Cancer is a class of diseases characterized by uncontrolled cell growth and has the ability to
spread or metastasize throughout the body. In recent years, remarkable progress has been …

Radiation-induced salivary gland dysfunction: mechanisms, therapeutics and future directions

KJ Jasmer, KE Gilman, K Muñoz Forti… - Journal of clinical …, 2020 - mdpi.com
Salivary glands sustain collateral damage following radiotherapy (RT) to treat cancers of the
head and neck, leading to complications, including mucositis, xerostomia and …

ICRU REPORT 96, dosimetry-guided radiopharmaceutical therapy

G Sgouros, WE Bolch, A Chiti… - Journal of the …, 2021 - journals.sagepub.com
The International Commission on Radiation Units and Measurements (ICRU), since its
inception in 1925, has had as its principal objective the development of internationally …

Second malignancies after radiotherapy for prostate cancer: systematic review and meta-analysis

CJD Wallis, AL Mahar, R Choo, S Herschorn… - bmj, 2016 - bmj.com
Objective To determine the association between exposure to radiotherapy for the treatment
of prostate cancer and subsequent second malignancies (second primary cancers). Design …

Radiation-induced bystander signalling in cancer therapy

KM Prise, JM O'sullivan - Nature Reviews Cancer, 2009 - nature.com
Our understanding of how radiation kills normal and tumour cells has been based on an
intimate knowledge of the direct induction of DNA damage and its cellular consequences …

The regulation of exosome secretion: a novel function of the p53 protein

X Yu, SL Harris, AJ Levine - Cancer research, 2006 - AACR
The p53 protein responds to stress signals by regulating the transcription of a variety of
genes. Some of these genes encode secreted proteins that may be involved in the …

MIRD pamphlet no. 22 (abridged): radiobiology and dosimetry of α-particle emitters for targeted radionuclide therapy

G Sgouros, JC Roeske, MR McDevitt… - Journal of nuclear …, 2010 - Soc Nuclear Med
The potential of α-particle emitters to treat cancer has been recognized since the early
1900s. Advances in the targeted delivery of radionuclides and radionuclide conjugation …

Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from α-particle irradiated to …

EI Azzam, SM De Toledo… - Proceedings of the …, 2001 - National Acad Sciences
It has generally been considered that important biological effects of ionizing radiation arise
as a direct consequence of DNA damage occurring in irradiated cells. We have examined …

Radiation carcinogenesis

JB Little - Carcinogenesis, 2000 - academic.oup.com
Research on radiation carcinogenesis during the past 2 decades has focused on cellular
and molecular mechanisms for the effects of radiation in mammalian cells. This paper will …

Non-targeted and Delayed Effects of Exposure to Ionizing Radiation: I. Radiation-Induced Genomic Instability and Bystander Effects In Vitro

WF Morgan - Radiation research, 2003 - meridian.allenpress.com
Morgan, W. Non-targeted and Delayed Effects of Exposure to Ionizing Radiation: I. Radiation-
Induced Genomic Instability and Bystander Effects In Vitro. Radiat. Res. 159, 567–580 …