An update on colorectal cancer microenvironment, epigenetic and immunotherapy

K Jin, C Ren, Y Liu, H Lan, Z Wang - International immunopharmacology, 2020 - Elsevier
Colorectal cancer (CRC) is considered as the second most common cancer worldwide. For
the past few years, the role of immunotherapy has been extensively studied and it has been …

Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy

M Chehelgerdi, F Behdarvand Dehkordi… - Molecular Cancer, 2023 - Springer
The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …

[PDF][PDF] An epigenetic signature of advanced colorectal cancer metastasis

EJ Rodger, G Gimenez, P Ajithkumar, PA Stockwell… - IScience, 2023 - cell.com
Colorectal cancer (CRC) is a leading cause of morbidity and mortality worldwide. The
majority of CRC deaths are caused by tumor metastasis, even following treatment. There is …

Association between Epstein-Bar virus and colorectal cancer: a systematic review and meta-analysis

EJ Maskouni, T Jamalvandi, F Tabatabaei… - Microbial …, 2023 - Elsevier
Aim This study aimed to investigate the prevalence and any potential association between
Epstein-Barr virus (EBV) infection and colorectal cancer (CRC). Methods A systematic …

Development and validation of an immune-related gene pairs signature in colorectal cancer

J Wu, Y Zhao, J Zhang, Q Wu, W Wang - Oncoimmunology, 2019 - Taylor & Francis
Although the outcome of colorectal cancer (CRC) patients has improved significantly with
the recent implementation of annual screening programs, reliable prognostic biomarkers are …

Molecular biomarkers for an early diagnosis, effective treatment and prognosis of colorectal cancer: Current updates

A Mahasneh, F Al-Shaheri, E Jamal - Experimental and molecular …, 2017 - Elsevier
Colorectal cancer (CRC) is the third most prevalent cancer in the world. Globally, it has been
estimated that about 1.4 million new cases of colorectal cancer are diagnosed every year …

The role of epigenetic therapies in colorectal cancer

M Baretti, NS Azad - Current problems in cancer, 2018 - Elsevier
Although developments in the diagnosis and therapy of colorectal cancer (CRC) have been
made in the last decade, much work remains to be done as it remains the second leading …

Sensitive detection of colorectal cancer in peripheral blood by a novel methylation assay

Y Zhang, Q Wu, L Xu, H Wang, X Liu, S Li, T Hu… - Clinical …, 2021 - Springer
Background Colorectal cancer (CRC) is a leading cause of cancer-related deaths
worldwide. Early detection of CRC can significantly reduce its mortality rate. Current method …

Epigenetic and epitranscriptomic changes in colorectal cancer: Diagnostic, prognostic, and treatment implications

E Porcellini, N Laprovitera, M Riefolo, M Ravaioli… - Cancer letters, 2018 - Elsevier
A cancer cell is the final product of a complex mixture of genetic, epigenetic and
epitranscriptomic alterations, whose final interplay contribute to cancer onset and …

27-hydroxycholesterol decreases cell proliferation in colon cancer cell lines

J Warns, G Marwarha, N Freking, O Ghribi - Biochimie, 2018 - Elsevier
Colorectal cancer (CRC) is the third most diagnosed cancer in the western world, affecting 1
out of approximately 22 people in their lifetime. Several epidemiological studies suggest a …