Testicular cancer (TC) is one of the most frequently incident solid tumors in males. A growing
prevalence has been documented in developed countries. Although recent advances have …

In mammals, male gametes are produced inside the testis by spermatogenesis, which has
three phases: mitotic proliferation of spermatogonia, meiosis of spermatocytes, and haploid …

MicroRNAs (miRNAs) are active regulators of numerous biological and physiological
processes including most of the events of mammalian reproduction. Understanding the …

Objective To determine the molecular characteristics of human spermatogonia and optimize
methods to enrich spermatogonial stem cells (SSCs). Design Laboratory study using human …

Abstract Background Small RNAs present in bovine ejaculate can be linked to sperm
abnormalities and fertility disorders. At present, quality parameters routinely used in semen …

The World Health Organization predicts that infertility will be the third major health threat
after cancer and cardiovascular disease, and will become a hot topic in medical research …

Mammalian spermatogenesis contains three continuous and organized processes, by which
spermatogonia undergo mitosis and differentiate to spermatocytes, follow on meiosis to form …

MicroRNAs applications were vastly studied throughout the years, spanning from potential
cancer biomarkers to targeted therapies for various diseases. Out of these utilizations, this …

Male fertility requires the continual production of sperm by the process of spermatogenesis.
This process requires the correct timing of regulatory signals to germ cells during each …

Abstract miRNAs play important roles during mammalian spermatogenesis. However, the
function of most miRNAs in spermatogenesis and the underlying mechanisms remain …