There are multiple assays available that can provide insight into the biochemical mechanism
of DNA helicases. For the first 22 years since their discovery, bulk-phase assays were used …

DNA helicases use energy derived from nucleoside 5′-triphosphate hydrolysis to catalyze
the separation of double-stranded DNA into single-stranded intermediates for replication …

Fluorescently labeled oligonucleotides are powerful tools for characterizing DNA processes;
however, their use is limited by the cost and sequence requirements of current labeling …

The integrity of the genetic information is dependent on the fidelity of DNA replication and
several DNA repair processes. Among these repair systems, DNA mismatch repair (MMR) is …

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