Ovarian cancer (OC) is one of the leading causes of cancer-related deaths in women. Most
patients are diagnosed with advanced epithelial OC in their late 60s, and early-onset adult …

Fanconi anemia (FA) is characterized by physical abnormalities, bone marrow failure, and
increased risk for malignancy. Physical abnormalities, present in approximately 75% of …

In childhood cancer, the frequency of cancer-associated germline variants and their
inheritance patterns are not thoroughly investigated. Moreover, the identification of children …

Germ line predisposition in acute myeloid leukemia (AML) has gained attention in recent
years because of a nonnegligible frequency and an impact on management of patients and …

Abstract Background/Aim: Germline copy number variation (CNV) is a type of genetic variant
that predisposes significantly to inherited cancers. Today, next-generation sequencing …

Accurate and complete genome duplication is crucial to maintain cell survival and prevent
malignant transformation. The Fanconi anemia (FA) pathway has traditionally been …

Objectives: Identify the etiology of Fanconi anemia. Describe the appropriate evaluation of
Fanconi anemia. Outline the management options available for Fanconi anemia. Summarize …

Prostate cancer is one of the leading causes of death among men worldwide, and thus,
research on the genetic factors enabling the formation of treatment-resistant cancer cells is …

Abstract Background Four Fanconi anemia (FA) genes (BRCA1, BRCA2, PALB2 and
RAD51C) are defined as breast cancer (BC) susceptibility genes. Other FA genes have …

Background Ameloblastic carcinoma and metastasising ameloblastoma are rare epithelial
odontogenic tumours with aggressive features. Distinguishing between these two lesions is …