Issues Relapse is a theoretical construct and empirical object of inquiry. It is unclear how
relapse is operationalised with regard to the various phases in substance use disorders …

Objective: Cannabis use is common among individuals with opioid use disorder, but it
remains unclear whether cannabis use is associated with an increase or a reduction in illicit …

Buprenorphine is one of three medications approved by the US Food and Drug
Administration (FDA) for opioid use disorder. Its efficacy is due to its partial agonist activity at …

Background Opioid-related deaths continue to increase to unprecedented rates in many
regions of the world. While long-term stable treatment has been shown to reduce associated …

Background and aims Longitudinal studies have revealed that substance use treatment use
is often recurrent among patients; the longitudinal patterns and characteristics of those …

Over 20 years ago, 615 people with heroin dependence in Australia joined me in what
would become one of our longest follow-up studies (1, 2). Thankfully, the vast majority …

Abstract The United States faces numerous challenges associated with the ongoing opioid
crisis. Although the opioid epidemic is complex, opioid overuse affects users' health and has …

Since the late 1990's, the US has been struggling with an epidemic linked to the use of
opiate drugs and their synthetic counterparts. While many have died in this epidemic, many …

According to 2021 data from the National Survey on Drug Use and Health (NSDUH), 16.5%
of the United States population over the age of 12 meet criteria for a substance use disorder …

Heroin use continues to result in significant harm to the health of individuals, including
dependence, blood borne viral infection transmission [1], and fatal and non-fatal overdose …