MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by
degrading or repressing the translation of their target messenger RNAs. As miRNAs are …

Renal fibrosis is the final pathological process common to any ongoing, chronic kidney
injury or maladaptive repair. It is considered as the underlying pathological process of …

Tubulointerstitial fibrosis is a chronic and progressive process affecting kidneys during aging
and in chronic kidney disease (CKD), regardless of cause. CKD and renal fibrosis affect half …

Acute kidney injury (AKI) is a major public health concern associated with high morbidity and
mortality. Despite decades of research, the pathogenesis of AKI remains incompletely …

Acute kidney injury (AKI) is an important health issue concerning∼ 50% of patients treated
in intensive care units. AKI mainly occurs after sepsis, acute ischemia, nephrotoxicity, or …

Abstract Expression of microRNA (miR)-126 is enriched in endothelial cells (ECs) and
endothelial progenitor cells (EPCs). MiR-126 is considered a master regulator of …

Platelet microparticles (MPs) represent the most abundant MPs subtype in the circulation,
and can mediate intercellular communication through delivery of bioactives molecules, such …

Progressive renal diseases are associated with rarefaction of peritubular capillaries, but the
ultrastructural and functional alterations of the microvasculature are not well described. To …

The pathogenesis of ischemic diseases remains unclear. Here we demonstrate the
induction of microRNA-668 (miR-668) in ischemic acute kidney injury (AKI) in human …

Mesenchymal stem cells (MSC s) have been considered as an attractive tool for the therapy
of diseases. Accumulating evidence indicates that the healing effects of MSC s are mainly …