Oxidized high-density lipoprotein as a risk factor for cardiovascular events in prevalent hemodialysis patients

H Honda, M Ueda, S Kojima, S Mashiba, T Michihata… - Atherosclerosis, 2012 - Elsevier
BACKGROUND AND OBJECTIVES: Here, we assessed the impact of oxidized high-density
lipoprotein (oxHDL), dysfunctional HDL, on mortality and cardiovascular disease (CVD) …

Activation of aldehyde dehydrogenase 2 slows down the progression of atherosclerosis via attenuation of ER stress and apoptosis in smooth muscle cells

M Yang, Y Wang, B Han, B Yang, Y Qiang… - Acta Pharmacologica …, 2018 - nature.com
Abstract Aldehyde dehydrogenase 2 (ALDH2) is a key mitochondrial enzyme in the
metabolism of aldehydes and may have beneficial cardiovascular effects for conditions such …

S1P in HDL promotes interaction between SR-BI and S1PR1 and activates S1PR1-mediated biological functions: calcium flux and S1PR1 internalization

MH Lee, KM Appleton, HM El-Shewy… - Journal of lipid …, 2017 - ASBMB
HDL normally transports about 50–70% of plasma sphingosine 1-phosphate (S1P), and the
S1P in HDL reportedly mediates several HDL-associated biological effects and signaling …

Effects of high-amount–high-intensity exercise on in vivo platelet activation: Modulation by lipid peroxidation and AGE/RAGE axis

F Santilli, N Vazzana, P Iodice… - Thrombosis and …, 2013 - thieme-connect.com
Physical activity is associated with cardiovascular risk reduction, but the effects of exercise
on platelet activation remain controversial. We investigated the effects of regular high …

[HTML][HTML] Human pericoronary adipose tissue as storage and possible supply site for oxidized low-density lipoprotein and high-density lipoprotein in coronary artery

Y Uchida, Y Uchida, E Shimoyama, N Hiruta… - Journal of …, 2017 - Elsevier
Background Thickening of the pericoronary adipose tissue (PCAT) is a proven risk factor for
coronary artery disease, but it is poorly understood whether PCAT stores pro-atherogenic …

Antihypercholesterolemic and antioxidant efficacies of zerumbone on the formation, development, and establishment of atherosclerosis in cholesterol-fed rabbits

HO Hemn, MM Noordin, HS Rahman… - Drug Design …, 2015 - Taylor & Francis
Owing to the high incidence of cholesterol-induced cardiovascular disease, particularly
atherosclerosis, the current study was designed to investigate the preventive and …

Regulation of lipid disorders by ethanol extracts from Zingiber zerumbet in high-fat diet-induced rats

CJ Chang, TF Tzeng, SS Liou, YS Chang, IM Liu - Food Chemistry, 2012 - Elsevier
The aim of this study was to investigate the antihyperlipidaemic effects of the ethanol extract
of Zingiber zerumbet (L) Smith (EEZZ). After being fed a high-fat diet (HFD) for 2weeks, rats …

Influence of dietary supplementation with Bacillus‐fermented adlay on lipid metabolism, antioxidant status and intestinal microflora in hamsters

CY Wang, HT Lin, SC Wu - Journal of the Science of Food and …, 2011 - Wiley Online Library
BACKGROUND: The effects of polished and dehulled Bacillus‐fermented adlay on lipid
metabolism, antioxidant status and intestinal microflora were examined in hyperlipidaemic …

Hyperlipidemia‐induced hepatic and small intestine ER stress and decreased paraoxonase 1 expression and activity is associated with HDL dysfunction in Syrian …

CS Stancu, MG Carnuta, GM Sanda… - Molecular nutrition & …, 2015 - Wiley Online Library
Scope We aimed at investigating the mechanisms linking hyperlipidemia (HL) with
dysfunctional HDL and its main antioxidant enzyme, paraoxonase1 (PON1). PON1 …

Mean platelet volume is elevated in patients with low high-density lipoprotein cholesterol

E Varol, F Aksoy, HA Bas, H Ari, M Ozaydin - Angiology, 2014 - journals.sagepub.com
A low high-density lipoprotein cholesterol (HDL-C) level is a predictor of increased
cardiovascular risk. We assessed the mean platelet volume (MPV) in patients with low HDL …