Enhanced SARS-CoV-2 neutralization by dimeric IgA

Z Wang, JCC Lorenzi, F Muecksch, S Finkin… - Science translational …, 2021 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes
coronavirus disease 2019 (COVID-19), primarily infects cells at mucosal surfaces. Serum …

Humoral response to the Pfizer BNT162b2 vaccine in patients undergoing maintenance hemodialysis

A Grupper, N Sharon, T Finn, R Cohen… - Clinical Journal of the …, 2021 - journals.lww.com
Results All subjects in the control group developed an antibody response compared with
96%(54 of 56) positive responders in the dialysis group. The IgG levels in the dialysis group …

Prospects for durable immune control of SARS-CoV-2 and prevention of reinfection

D Cromer, JA Juno, D Khoury, A Reynaldi… - Nature Reviews …, 2021 - nature.com
Immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is
central to long-term control of the current pandemic. Despite our rapidly advancing …

Impaired humoral immunity to SARS-CoV-2 BNT162b2 vaccine in kidney transplant recipients and dialysis patients

H Rincon-Arevalo, M Choi, AL Stefanski, F Halleck… - Science …, 2021 - science.org
Patients with kidney failure are at increased risk of SARS-CoV-2 infection, making effective
vaccinations a critical need. It is not known how well mRNA vaccines induce B and plasma …

Immunogenicity of the BNT162b2 COVID-19 mRNA vaccine and early clinical outcomes in patients with haematological malignancies in Lithuania: a national …

K Maneikis, K Šablauskas, U Ringelevičiūtė… - The Lancet …, 2021 - thelancet.com
Background Haematological malignancies and their treatments are likely to affect SARS-
CoV-2 vaccine efficacy. We aimed to evaluate serological response to BNT162b2 vaccine in …

[HTML][HTML] Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies

AJ Greaney, AN Loes, KHD Crawford, TN Starr… - Cell host & …, 2021 - cell.com
The evolution of SARS-CoV-2 could impair recognition of the virus by human antibody-
mediated immunity. To facilitate prospective surveillance for such evolution, we map how …

Large-scale study of antibody titer decay following BNT162b2 mRNA vaccine or SARS-CoV-2 infection

A Israel, Y Shenhar, I Green, E Merzon, A Golan-Cohen… - Vaccines, 2021 - mdpi.com
Immune protection following either vaccination or infection with SARS-CoV-2 is thought to
decrease over time. We designed a retrospective study, conducted at Leumit Health …

Association of SARS-CoV-2 seropositive antibody test with risk of future infection

RA Harvey, JA Rassen, CA Kabelac… - JAMA internal …, 2021 - jamanetwork.com
Importance Understanding the effect of serum antibodies to severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) on susceptibility to infection is important for …

Evolution of antibody responses up to 13 months after SARS-CoV-2 infection and risk of reinfection

F Gallais, P Gantner, T Bruel, A Velay, D Planas… - …, 2021 - thelancet.com
Background Assessment of the kinetics of SARS-CoV-2 antibodies is essential in predicting
risk of reinfection and durability of vaccine protection. Methods This is a prospective …

SARS-CoV-2-specific T cells in infection and vaccination

A Bertoletti, N Le Bert, M Qui, AT Tan - Cellular & molecular …, 2021 - nature.com
During viral infections, antibodies and T cells act together to prevent pathogen spread and
remove virus-infected cells. Virus-specific adaptive immunity can, however, also trigger …