Role of senescence and aging in SARS-CoV-2 infection and COVID-19 disease

SM Lynch, G Guo, DS Gibson, AJ Bjourson, TS Rai - Cells, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has resulted in a global pandemic associated with substantial …

Adaptive immune determinants of viral clearance and protection in mouse models of SARS-CoV-2

B Israelow, T Mao, J Klein, E Song, B Menasche… - Science …, 2021 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused more than 160
million infections and more than 3 million deaths worldwide. Although effective vaccines are …

Of bats and men: Immunomodulatory treatment options for COVID-19 guided by the immunopathology of SARS-CoV-2 infection

MJ Christie, AT Irving, SC Forster, BJ Marsland… - Science …, 2021 - science.org
In humans, SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is highly
infective, often causes severe acute and/or long-term illness, and elicits a high rate of …

Lower persistence of anti-nucleocapsid compared to anti-spike antibodies up to one year after SARS-CoV-2 infection

J Van Elslande, M Oyaert, N Lorent… - … and infectious disease, 2022 - Elsevier
We retrospectively compared the long-term evolution of IgG anti-spike (S) and anti-
nucleocapsid (N) levels (Abbott immunoassays) in 116 non-severe and 115 severe SARS …

[HTML][HTML] Anti-spike antibody response to natural SARS-CoV-2 infection in the general population

J Wei, PC Matthews, N Stoesser, T Maddox… - Nature …, 2021 - nature.com
Understanding the trajectory, duration, and determinants of antibody responses after SARS-
CoV-2 infection can inform subsequent protection and risk of reinfection, however large …

Necessity of coronavirus disease 2019 (COVID-19) vaccination in persons who have already had COVID-19

NK Shrestha, PC Burke, AS Nowacki… - Clinical Infectious …, 2022 - academic.oup.com
Background The aim was to evaluate the necessity of coronavirus disease 2019 (COVID-19)
vaccination in persons with prior COVID-19. Methods Employees of the Cleveland Clinic …

Persistence of antibody and cellular immune responses in coronavirus disease 2019 patients over nine months after infection

L Yao, GL Wang, Y Shen, ZY Wang… - The Journal of …, 2021 - academic.oup.com
Background The duration of humoral and T and B cell response after the infection of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains unclear. Methods We …

Age and smoking predict antibody titres at 3 months after the second dose of the BNT162b2 COVID-19 vaccine

Y Nomura, M Sawahata, Y Nakamura, M Kurihara… - Vaccines, 2021 - mdpi.com
Objective: We aimed to determine antibody (Ab) titres 3 months after the second dose of the
BNT162b2 coronavirus disease-2019 (COVID-19) vaccine and to explore clinical variables …

Declining levels of neutralizing antibodies against SARS-CoV-2 in convalescent COVID-19 patients one year post symptom onset

T Xiang, B Liang, Y Fang, S Lu, S Li, H Wang… - Frontiers in …, 2021 - frontiersin.org
Major advances have been made in understanding the dynamics of humoral immunity
briefly after the acute coronavirus disease 2019 (COVID-19). However, knowledge …

Quantifying the risk of SARS‐CoV‐2 reinfection over time

EO Murchu, P Byrne, PG Carty… - Reviews in medical …, 2022 - Wiley Online Library
Despite over 140 million SARS‐CoV‐2 infections worldwide since the beginning of the
pandemic, relatively few confirmed cases of SARS‐CoV‐2 reinfection have been reported …