Central nervous system (CNS) accumulation of fibrillary deposits made of Amyloid β (A β),
hyperphosphorylated Tau or α-synuclein (α-syn), present either alone or in the form of mixed …

The brain endothelial cell (BEC) glycocalyx (ecGCx) is a BEC surface coating consisting of a
complex interwoven polysaccharide (sweet husk) mesh-like network of membrane-bound …

Background The glymphatic system is reportedly involved in Parkinson's disease (PD).
Based on previous studies, we aimed to confirm the correlation between the glymphatic …

Embryonic genetic mechanisms are present in the brain and ready to be placed into action
upon cellular injury, termed the response to injury wound-healing (RTIWH) mechanism …

Brain capillary endothelial cell (s)(BECs) have numerous functions, including their
semipermeable interface-barrier (transfer and diffusion of solutes), trophic (metabolic …

The recently described perivascular unit (PVU) resides immediately adjacent to the true
capillary neurovascular unit (NVU) in the postcapillary venule and contains the normal …

Astrocytes (ACs) are the most abundant cells in the brain and, importantly, are the master
connecting and communicating cells that provide structural and functional support for brain …

Globally, cerebral microbleeds (CMBs) are increasingly being viewed not only as a marker
for cerebral small vessel disease (SVD) but also as having an increased risk for the …

The disruption of the blood–brain barrier (BBB) in Alzheimer's Disease (AD) is largely
influenced by amyloid beta (Aβ). In this study, we developed a high-throughput microfluidic …

Pericyte (s)(Pcs) and resident perivascular macrophages (rPVMΦs) are positioned perfectly
in the neurovascular unit (NVU) and perivascular spaces to facilitate metainflammation that …