Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models
Emergence of SARS-CoV-2 variants of concern (VOCs), including the highly transmissible
Omicron and Delta strains, has posed constant challenges to the current COVID-19 vaccines …
Omicron and Delta strains, has posed constant challenges to the current COVID-19 vaccines …
Increased resistance of SARS-CoV-2 Omicron variant to neutralization by vaccine-elicited and therapeutic antibodies
T Tada, H Zhou, BM Dcosta, MI Samanovic… - …, 2022 - thelancet.com
Background SARS-CoV-2 vaccines currently authorized for emergency use have been
highly successful in preventing infection and lessening disease severity. The vaccines …
highly successful in preventing infection and lessening disease severity. The vaccines …
[HTML][HTML] Omicron variant (B. 1.1. 529) and its sublineages: What do we know so far amid the emergence of recombinant variants of SARS-CoV-2?
M Dhawan, ARA Saied, S Mitra, FA Alhumaydhi… - Biomedicine & …, 2022 - Elsevier
Since the start of the COVID-19 pandemic, numerous variants of SARS-CoV-2 have been
reported worldwide. The advent of variants of concern (VOCs) raises severe concerns amid …
reported worldwide. The advent of variants of concern (VOCs) raises severe concerns amid …
An early warning system for emerging SARS-CoV-2 variants
An early warning system for emerging SARS-CoV-2 variants | Nature Medicine Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …
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SARS-CoV-2 BA. 1 variant is neutralized by vaccine booster–elicited serum but evades most convalescent serum and therapeutic antibodies
S Lusvarghi, SD Pollett, SN Neerukonda… - Science Translational …, 2022 - science.org
The rapid spread of the highly contagious Omicron variant of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) along with its high number of mutations in the spike …
syndrome coronavirus 2 (SARS-CoV-2) along with its high number of mutations in the spike …
Compensatory epistasis maintains ACE2 affinity in SARS-CoV-2 Omicron BA. 1
The Omicron BA. 1 variant emerged in late 2021 and quickly spread across the world.
Compared to the earlier SARS-CoV-2 variants, BA. 1 has many mutations, some of which …
Compared to the earlier SARS-CoV-2 variants, BA. 1 has many mutations, some of which …
[HTML][HTML] Omicron severity: milder but not mild
J Nealon, BJ Cowling - Lancet (London, England), 2022 - ncbi.nlm.nih.gov
In The Lancet, Nicole Wolter and colleagues1 report data from more than 11 000 individuals
(> 80· 0% aged 19–59 years; 55· 9% women) with COVID-19 in South Africa indicative of …
(> 80· 0% aged 19–59 years; 55· 9% women) with COVID-19 in South Africa indicative of …
[PDF][PDF] Structural and functional impact by SARS-CoV-2 Omicron spike mutations
The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
bearing an unusually high number of mutations, has become a dominant strain in many …
bearing an unusually high number of mutations, has become a dominant strain in many …
Prior vaccination promotes early activation of memory T cells and enhances immune responses during SARS-CoV-2 breakthrough infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of vaccinated
individuals is increasingly common but rarely results in severe disease, likely due to the …
individuals is increasingly common but rarely results in severe disease, likely due to the …
[PDF][PDF] Protective prototype-Beta and Delta-Omicron chimeric RBD-dimer vaccines against SARS-CoV-2
K Xu, P Gao, S Liu, S Lu, W Lei, T Zheng, X Liu, Y Xie… - Cell, 2022 - cell.com
Breakthrough infections by SARS-CoV-2 variants become the global challenge for
pandemic control. Previously, we developed the protein subunit vaccine ZF2001 based on …
pandemic control. Previously, we developed the protein subunit vaccine ZF2001 based on …