The SARS-CoV-2 Omicron (B. 1.1529) variant was designated as a variant of concern (VOC)
by the World Health Organization (WHO) on November 26, 2021. Within two months, it had …

The continual evolution of SARS-CoV-2 and the emergence of variants that show resistance
to vaccines and neutralizing antibodies threaten to prolong the COVID-19 pandemic …

T cell responses play an important role in protection against beta-coronavirus infections,
including SARS-CoV-2, where they associate with decreased COVID-19 disease severity …

At the end of 2021 a new SARS-CoV-2 variant, Omicron, emerged and quickly spread
across the world. It has been demonstrated that Omicron's high number of Spike mutations …

Vaccines based on the spike protein of SARS-CoV-2 are a cornerstone of the public health
response to COVID-19. The emergence of hypermutated, increasingly transmissible variants …

Multiple BA. 4 and BA. 5 subvariants with Arg346 mutations in the spike glycoprotein have
been identified in various countries, such as BA. 4.6, BF. 7, BA. 5.2. 6, BA. 4.1. 9, and BE. 1.2 …

Omicron, the great escape artist Page 1 NATuRe RevIeWS | ImmunOlOgy 0123456789();:
immune functions seem to be markedly disrupted in macrophages from older mice. Additional …

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) constitutes a major worldwide public health threat …

During the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic,
multiple variants escaping preexisting immunity emerged, causing reinfections of previously …

The persistent COVID-19 pandemic since 2020 has brought an enormous public health
burden to the global society and is accompanied by various evolution of the virus genome …