COVID-19: challenges of viral variants
JL Jacobs, G Haidar, JW Mellors - Annual Review of Medicine, 2023 - annualreviews.org
The COVID-19 pandemic has been accompanied by SARS-CoV-2 evolution and
emergence of viral variants that have far exceeded initial expectations. Five major variants of …
emergence of viral variants that have far exceeded initial expectations. Five major variants of …
[PDF][PDF] Rational identification of potent and broad sarbecovirus-neutralizing antibody cocktails from SARS convalescents
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages have
escaped most receptor-binding domain (RBD)-targeting therapeutic neutralizing antibodies …
escaped most receptor-binding domain (RBD)-targeting therapeutic neutralizing antibodies …
Immune evasion and ACE2 binding affinity contribute to SARS-CoV-2 evolution
Mutations in the SARS-CoV-2 genome could confer resistance to pre-existing antibodies
and/or increased transmissibility. The recently emerged Omicron subvariants exhibit a …
and/or increased transmissibility. The recently emerged Omicron subvariants exhibit a …
Virological characteristics of SARS-CoV-2 BA. 2 variant
D Yamasoba, I Kimura, H Nasser, Y Morioka, N Nao… - BioRxiv, 2022 - biorxiv.org
Soon after the emergence and global spread of a new severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) Omicron lineage, BA. 1 (ref,), another Omicron lineage, BA. 2 …
coronavirus 2 (SARS-CoV-2) Omicron lineage, BA. 1 (ref,), another Omicron lineage, BA. 2 …
[HTML][HTML] A detailed overview of immune escape, antibody escape, partial vaccine escape of SARS-CoV-2 and their emerging variants with escape mutations
The infective SARS-CoV-2 is more prone to immune escape. Presently, the significant
variants of SARS-CoV-2 are emerging in due course of time with substantial mutations …
variants of SARS-CoV-2 are emerging in due course of time with substantial mutations …
Effectiveness of inactivated and Ad5-nCoV COVID-19 vaccines against SARS-CoV-2 Omicron BA. 2 variant infection, severe illness, and death
Z Huang, S Xu, J Liu, L Wu, J Qiu, N Wang, J Ren, Z Li… - BMC medicine, 2022 - Springer
Background Limited data are available on the effectiveness of inactivated and Ad5-nCoV
COVID-19 vaccines in real-world use—especially against Omicron variants in SARS-CoV-2 …
COVID-19 vaccines in real-world use—especially against Omicron variants in SARS-CoV-2 …
Inactivated vaccine-elicited potent antibodies can broadly neutralize SARS-CoV-2 circulating variants
Y Liu, Z Wang, X Zhuang, S Zhang, Z Chen… - Nature …, 2023 - nature.com
A full understanding of the inactivated COVID-19 vaccine-mediated antibody responses to
SARS-CoV-2 circulating variants will inform vaccine effectiveness and vaccination …
SARS-CoV-2 circulating variants will inform vaccine effectiveness and vaccination …
Deep-learning-enabled protein–protein interaction analysis for prediction of SARS-CoV-2 infectivity and variant evolution
G Wang, X Liu, K Wang, Y Gao, G Li… - Nature Medicine, 2023 - nature.com
Host–pathogen interactions and pathogen evolution are underpinned by protein–protein
interactions between viral and host proteins. An understanding of how viral variants affect …
interactions between viral and host proteins. An understanding of how viral variants affect …
Germline-encoded amino acid–binding motifs drive immunodominant public antibody responses
EL Shrock, RT Timms, T Kula, EL Mena, AP West Jr… - Science, 2023 - science.org
Despite the vast diversity of the antibody repertoire, infected individuals often mount
antibody responses to precisely the same epitopes within antigens. The immunological …
antibody responses to precisely the same epitopes within antigens. The immunological …
[HTML][HTML] Genomic surveillance for SARS-CoV-2 variants: circulation of omicron lineages—United States, January 2022–May 2023
KC Ma - MMWR. Morbidity and Mortality Weekly Report, 2023 - cdc.gov
Genomic Surveillance for SARS-CoV-2 Variants: Circulation of Omicron Lineages — United
States, January 2022–May 2023 | MMWR Skip directly to site content Skip directly to search …
States, January 2022–May 2023 | MMWR Skip directly to site content Skip directly to search …