The 5th edition of the World Health Organization classification of haematolymphoid tumours: lymphoid neoplasms

R Alaggio, C Amador, I Anagnostopoulos, AD Attygalle… - Leukemia, 2022 - nature.com
We herein present an overview of the upcoming 5th edition of the World Health Organization
Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid …

Acute lymphoblastic leukaemia

F Malard, M Mohty - The Lancet, 2020 - thelancet.com
Acute lymphoblastic leukaemia develops in both children and adults, with a peak incidence
between 1 year and 4 years. Most acute lymphoblastic leukaemia arises in healthy …

The evolution of acute lymphoblastic leukemia research and therapy at MD Anderson over four decades

E Jabbour, NJ Short, N Jain, FG Haddad… - Journal of Hematology & …, 2023 - Springer
Progress in the research and therapy of adult acute lymphoblastic leukemia (ALL) is
accelerating. This analysis summarizes the data derived from the clinical trials conducted at …

A pediatric regimen for older adolescents and young adults with acute lymphoblastic leukemia: results of CALGB 10403

W Stock, SM Luger, AS Advani, J Yin… - Blood, The Journal …, 2019 - ashpublications.org
Retrospective studies have suggested that older adolescents and young adults (AYAs) with
acute lymphoblastic leukemia (ALL) have better survival rates when treated using a pediatric …

Genetic basis of acute lymphoblastic leukemia

I Iacobucci, CG Mullighan - Journal of Clinical Oncology, 2017 - ascopubs.org
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, and despite cure
rates exceeding 90% in children, it remains an important cause of morbidity and mortality in …

The genetic basis and cell of origin of mixed phenotype acute leukaemia

TB Alexander, Z Gu, I Iacobucci, K Dickerson, JK Choi… - Nature, 2018 - nature.com
Mixed phenotype acute leukaemia (MPAL) is a high-risk subtype of leukaemia with myeloid
and lymphoid features, limited genetic characterization, and a lack of consensus regarding …

Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia

LE Montefiori, S Bendig, Z Gu, X Chen, P Pölönen… - Cancer discovery, 2021 - AACR
Lineage-ambiguous leukemias are high-risk malignancies of poorly understood genetic
basis. Here, we describe a distinct subgroup of acute leukemia with expression of myeloid, T …

Ph-like acute lymphoblastic leukemia: a high-risk subtype in adults

N Jain, KG Roberts, E Jabbour, K Patel… - Blood, The Journal …, 2017 - ashpublications.org
Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL) is a high-risk
subtype of ALL in children. There are conflicting data on the incidence and prognosis of Ph …

Philadelphia chromosome–like acute lymphoblastic leukemia

SK Tasian, ML Loh, SP Hunger - Blood, The Journal of the …, 2017 - ashpublications.org
Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL), also referred to as
BCR-ABL1–like ALL, is a high-risk subset with a gene expression profile that shares …

Targetable kinase gene fusions in high-risk B-ALL: a study from the Children's Oncology Group

SC Reshmi, RC Harvey, KG Roberts… - Blood, The Journal …, 2017 - ashpublications.org
Philadelphia chromosome-like (Ph-like) acute lymphoblastic leukemia (ALL) is a high-risk
subtype characterized by genomic alterations that activate cytokine receptor and kinase …