[HTML][HTML] Nanomaterials designed for antiviral drug delivery transport across biological barriers

FD Cojocaru, D Botezat, I Gardikiotis, CM Uritu, G Dodi… - Pharmaceutics, 2020 - mdpi.com
Viral infections are a major global health problem, representing a significant cause of
mortality with an unfavorable continuously amplified socio-economic impact. The increased …

[HTML][HTML] Nanocarriers for pancreatic cancer imaging, treatments, and immunotherapies

L Liu, PG Kshirsagar, SK Gautam, M Gulati, EI Wafa… - Theranostics, 2022 - ncbi.nlm.nih.gov
Pancreatic tumors are highly desmoplastic and immunosuppressive. Delivery and
distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and …

Treatment of neurodegenerative disorders through the blood–brain barrier using nanocarriers

N Poovaiah, Z Davoudi, H Peng, B Schlichtmann… - Nanoscale, 2018 - pubs.rsc.org
Neurodegenerative diseases refer to disorders of the central nervous system (CNS) that are
caused by neuronal degradations, dysfunctions, or death. Alzheimer's disease, Parkinson's …

[HTML][HTML] Disentangling mitochondria in Alzheimer's disease

A Johri - International journal of molecular sciences, 2021 - mdpi.com
Alzheimer's disease (AD) is a major cause of dementia in older adults and is fast becoming
a major societal and economic burden due to an increase in life expectancy. Age seems to …

Material solutions for delivery of CRISPR/Cas-based genome editing tools: Current status and future outlook

T Wan, D Niu, C Wu, FJ Xu, G Church, Y Ping - Materials Today, 2019 - Elsevier
Clustered regularly interspaced short palindromic repeat (CRISPR)/associated protein
(CRISPR/Cas) system is an adaptable immune mechanism used by many bacteria to protect …

Pharmacology of apocynin: a natural acetophenone

SR Savla, AP Laddha, YA Kulkarni - Drug metabolism reviews, 2021 - Taylor & Francis
Apocynin is a naturally occurring acetophenone, found in the roots of Apocynum
cannabinum and Picrorhiza kurroa. Various chemical and pharmaceutical modifications …

[HTML][HTML] Smart and multi-functional magnetic nanoparticles for cancer treatment applications: clinical challenges and future prospects

E Aram, M Moeni, R Abedizadeh, D Sabour… - Nanomaterials, 2022 - mdpi.com
Iron oxide nanoparticle (IONPs) have become a subject of interest in various biomedical
fields due to their magnetism and biocompatibility. They can be utilized as heat mediators in …

Polysorbate-coated mesoporous silica nanoparticles as an efficient carrier for improved rivastigmine brain delivery

SF Basharzad, M Hamidi, A Maleki, Z Karami… - Brain Research, 2022 - Elsevier
Targeted delivery of neurological therapeutic to the brain has been attracting more and more
attention to the treatment of central nervous system (CNS) diseases. Nonetheless, the main …

[HTML][HTML] Root System Architecture, Copper Uptake and Tissue Distribution in Soybean (Glycine max (L.) Merr.) Grown in Copper Oxide Nanoparticle (CuONP) …

E Yusefi-Tanha, S Fallah, A Rostamnejadi, LR Pokhrel - Plants, 2020 - mdpi.com
Understanding the potential uptake and biodistribution of engineered nanoparticles (ENPs)
in soil-grown plants is imperative for realistic toxicity and risk assessment considering the …

Nanoparticle-based diagnostic and therapeutic systems for brain tumors

X Wu, H Yang, W Yang, X Chen, J Gao… - Journal of Materials …, 2019 - pubs.rsc.org
Brain tumors, especially the most prevalent and aggressive glioblastoma, remain among the
deadliest of all types of cancer due to inefficient theranostic options. They have a limited …