Empowering radiotherapy: Harnessing nanomedicines to enhance radiation response and boost antitumor efficacy

X Zhuo, R Aishajiang, Y Liang, P Du, P Lei, D Yu… - Coordination Chemistry …, 2024 - Elsevier
Radiotherapy (RT) is a conventional form of tumor treatment that uses X-ray irradiation to
eliminate tumors. Although RT plays an important role in treating tumor patients and …

Redox Regulation of Immunometabolism in Microglia Underpinning Diabetic Retinopathy

L Cai, M Xia, F Zhang - Antioxidants, 2024 - mdpi.com
Diabetic retinopathy (DR) is the leading cause of visual impairment and blindness among
the working-age population. Microglia, resident immune cells in the retina, are recognized …

Inhibition of KIAA1429/HK1 axis enhances the sensitivity of liver cancer cells to sorafenib by regulating the Warburg effect

D Liu, M Shan, R Zeng, M He, X Dai, L Lu… - Biochemical …, 2024 - Elsevier
Abstract N6-methyladenosine (m6A) serves as the most abundant posttranscription
modification. However, the role of m6A in tumorigenesis and chemotherapeutic drugs …

Novel sulfonamide-indolinone hybrids targeting mitochondrial respiration of breast cancer cells

SWA Helmy, AK Abdel-Aziz, EME Dokla… - European Journal of …, 2024 - Elsevier
Breast cancer (BC) still poses a threat worldwide which demands continuous efforts to
present safer and efficacious treatment options via targeted therapy. Beside kinases' …

[HTML][HTML] Novel inhibitors targeting the PGK1 metabolic enzyme in glycolysis exhibit effective antitumor activity against kidney renal clear cell carcinoma in vitro and in …

Y He, Y Luo, L Huang, D Zhang, H Hou, Y Liang… - European Journal of …, 2024 - Elsevier
Our previous research has revealed phosphoglycerate kinase 1 (PGK1) enhances
tumorigenesis and sorafenib resistance of kidney renal clear cell carcinoma (KIRC) by …

PLA inhibits TNF-α-induced PANoptosis of prostate cancer cells through metabolic reprogramming

Y Hao, F Xie, J He, C Gu, Y Zhao, W Luo… - … International Journal of …, 2024 - Elsevier
Previous studies have shown that phenyllactic acid (alpha-Hydroxyhydrocinnamic acid, 2-
Hydroxy-3-phenylpropionic acid, PLA), a type of organic acid metabolite, has excellent …

Lysine methyltransferase 5C increases the proliferation and metastatic abilities of clear cell renal cell carcinoma via aerobic glycolysis

B Zeng, R Wan, K Chang, J Li… - International …, 2024 - spandidos-publications.com
Among all types of renal cancer, clear cell renal cell carcinoma (ccRCC) is the most common
and lethal subtype and is associated with a high risk of metastasis and recurrence. Histone …

Cytotoxicity Enhancement in Osteosarcoma with Multifunctional I-131 Radiotherapeutic Nanoparticles: In Vitro Three-Dimensional Spheroid Model and Release …

SK Marshall, M Taweesap, B Saelim, V Pachana… - Molecules, 2024 - mdpi.com
This novel radiolabeled chitosan nanoparticle, facilitated with curcumin, increased
doxorubicin cytotoxicity and radiosensitivity to MG-63 osteosarcoma cells in a three …

[HTML][HTML] UBE2T 通过调节性T 细胞诱导肝细胞癌的放疗抵抗

何欣容, 熊斯丽, 朱真如, 孙景苑… - Journal of Southern …, 2024 - ncbi.nlm.nih.gov
UBE2T通过调节性T细胞诱导肝细胞癌的放疗抵抗- PMC Back to Top Skip to main content NIH
NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation …

[PDF][PDF] The novel family of Warbicin® compounds inhibits glucose uptake both in yeast and human cells and restrains cancer cell proliferation

W Vanthienen, J Fernandez-Garcıa, MF Baietti… - yeast, 2024 - researchgate.net
Cells of many cancer types share with yeast cells a preference for fermentation over
respiration of glucose even under aerobic conditions and also in cancer types that have …