In the late 19th century, Otto Frank published the first description of a ventricular pressure-
volume diagram, thus laid the foundation for modern cardiovascular physiology. Since then …

Chronic heart failure (HF) is rare in the young and common in the elderly in the Western
world. HF in the young is usually due to specific causes, predominantly or exclusively …

Aims SARS‐CoV‐2 infection may lead to endothelial and vascular dysfunction. We
investigated alterations of arterial stiffness, endothelial coronary and myocardial function …

The SPARTE study (Strategy for Preventing cardiovascular and renal events based on
ARTErial stiffness; URL: https://www. clinicaltrials. gov; Unique identifier: NCT02617238) is a …

Background We investigated the effects of insulin, glucagon‐like peptide‐1 receptor
agonists (GLP‐1 RA), sodium‐glucose cotransporter‐2 inhibitors (SGLT‐2i), and their …

Hypertension constitutes a major risk factor for heart failure with preserved ejection fraction
(HFpEF). HFpEF is a prevalent clinical syndrome with increased cardiovascular morbidity …

Background Echocardiographic surrogates of right ventricle–to–pulmonary artery (RV-PA)
coupling have been reported to be associated with outcomes in patients with secondary …

Aims The present study sought to evaluate the correlation between indices of non-invasive
myocardial work (MW) and left ventricle (LV) size, traditional and advanced parameters of …

A precise and accurate assessment of left ventricular (LV) contractility is of utmost
importance in terms of prognosis in most cardiac pathologies. Given the limitations of …

Cardiovascular (CV) disease impacts tens of millions of people annually and carries a
massive global economic burden. Continued advances in medical imaging, hardware and …