[HTML][HTML] Genetic causes of spermatogenic failure

A Massart, W Lissens, H Tournaye… - Asian journal of …, 2012 - ncbi.nlm.nih.gov
Abstract Approximately 10%–15% of couples are infertile, and a male factor is involved in
almost half of these cases. This observation is due in part to defects in spermatogenesis …

Variations in antioxidant genes and male infertility

B Yu, Z Huang - BioMed research international, 2015 - Wiley Online Library
Oxidative stress and reactive oxygen species (ROS) are generated from both endogenous
and environmental resources, which in turn may cause defective spermatogenesis and male …

Smoking‐induced genetic and epigenetic alterations in infertile men

S Gunes, A Metin Mahmutoglu, MA Arslan… - Andrologia, 2018 - Wiley Online Library
Male fertility rates have shown a progressive decrease in both developing and industrialised
countries in the past 50 years. Clinical and epidemiological studies have demonstrated …

The association of glutathione-S-transferase gene polymorphisms (GSTM1, GSTT1, GSTP1) with idiopathic male infertility

MR Safarinejad, N Shafiei, S Safarinejad - Journal of Human Genetics, 2010 - nature.com
The effects of the GST genes (GSTM1, GSTT1 and GSTP1) on male factor infertility have not
been well elucidated. A case–control study was performed to investigate the association …

The triple role of glutathione S-transferases in mammalian male fertility

M Llavanera, Y Mateo-Otero, S Bonet… - Cellular and Molecular …, 2020 - Springer
Male idiopathic infertility accounts for 15–25% of reproductive failure. One of the factors that
has been linked to this condition is oxidative stress (OS), defined as the imbalance between …

GSTM1 and GSTT1 null polymorphisms and male infertility risk: an updated meta-analysis encompassing 6934 subjects

W Wu, J Lu, Q Tang, S Zhang, B Yuan, J Li, D Wu… - Scientific reports, 2013 - nature.com
Published data on the association between the GST genes polymorphisms and male
infertility risk are inconclusive. We investigated GST genes polymorphisms in a large sample …

[HTML][HTML] Array-based DNA methylation profiling reveals peripheral blood differential methylation in male infertility

S Sarkar, KM Sujit, V Singh, R Pandey, S Trivedi… - Fertility and …, 2019 - Elsevier
Objective To study peripheral blood DNA differential methylation in oligozoospermic infertile
men in comparison with normozoospermic fertile controls. Design Case-control study …

Joint effect of glutathione S‐transferase genotypes and cigarette smoking on idiopathic male infertility

SL Yarosh, EV Kokhtenko, MI Churnosov… - Andrologia, 2015 - Wiley Online Library
Inconsistent results of association studies investigated the role of glutathione S–transferase
genes in idiopathic male infertility may be explained by ethnical differences in gene–gene …

Rohypnol‐induced sexual dysfunction is via suppression of hypothalamic‐pituitary‐testicular axis: An experimental study in rats

DT Oluwole, RE Akhigbe, AF Ajayi - Andrologia, 2021 - Wiley Online Library
Sexual activity is an essential part of reproductive functions and needed for the maintenance
of fertility. Drugs, particularly substances of abuse, impair male reproductive function either …

[HTML][HTML] Basic and clinical genetic studies on male infertility in Iran during 2000-2016: A review

S Moghbelinejad, H Mozdarani… - International Journal …, 2018 - ncbi.nlm.nih.gov
The male factor contributes to 50% of infertility. The cause of male infertility is idiopathic and
could be congenital or acquired. Among different factors which are involved in idiopathic …