Canadian asthma consensus report, 1999

LP Boulet, A Becker, D Bérubé, R Beveridge, P Ernst… - Cmaj, 1999 - Can Med Assoc
Objectives: To provide physicians with current guidelines for the diagnosis and optimal
management of asthma in children and adults, including pregnant women and the elderly, in …

Interpretation of positive results of a methacholine inhalation challenge and 1 week of inhaled bronchodilator use in diagnosing and treating cough-variant asthma

RS Irwin, CT French, NA Smyrnios… - Archives of Internal …, 1997 - jamanetwork.com
Background: In diagnosing cough due to asthma, methacholine chloride inhalation
challenge (MIC) interpreted in a traditional fashion has been shown to have positive …

Nedocromil sodium: an updated review of its pharmacological properties and therapeutic efficacy in asthma

RN Brogden, EM Sorkin - Drugs, 1993 - Springer
Synopsis Nedocromil sodium, the disodium salt of a pyranoquinoline dicarboxylic acid, has
anti-inflammatory properties in vitro, in animal models of asthma, and in humans, as …

Nedocromil sodium is more effective than cromolyn sodium for the treatment of chronic reversible obstructive airway disease

S Lal, PD Dorow, KK Venho, SS Chatterjee - Chest, 1993 - Elsevier
In a multicenter, double-blind, group comparative trial, the efficacy of nedocromil sodium
(nedocromil, 4 mg, four times daily [qid]), cromolyn sodium (2 mg, qid), and placebo was …

The clinical efficacy of inhaled nedocromil sodium (Tilade) in the treatment of asthma

AM Edwards, MT Stevens - European Respiratory Journal, 1993 - Eur Respiratory Soc
Inhaled nedocromil sodium, an anti-inflammatory agent for the maintenance treatment of
asthma, has been the subject of many clinical trials but only a proportion have been …

Effect of nedocromil sodium on airway sensory nerves

PJ Barnes - Journal of allergy and clinical immunology, 1993 - Elsevier
There is increasing evidence that the sensory nerves of the airway play a role in the
asthmatic response. Nerve endings are exposed by the epithelial shedding that occurs with …

Comparison of nedocromil sodium at two dosage frequencies with placebo in the management of chronic asthma

A Wells, C Drennan, P Holst, D Jones, H Rea… - Respiratory …, 1992 - Elsevier
Nedocromil sodium (4 mg bd or qid) was added to the therapy of 76chronic asthmatic
patients in a four-centre, double-blind cross-over, placebo-controlled trial. Patients had …

Nedocromil sodium versus albuterol in the management of allergic asthma.

JW De Jong, JP Teengs, DS Postma… - American journal of …, 1994 - atsjournals.org
In a double-blind, double-placebo, randomized crossover study, we compared the effects of
6 wk of treatment with the anti-inflammatory drug nedocromil sodium (16 mg/day) with 6 wk …

Nedocromil sodium and sodium cromoglycate in patients aged over 50 years with asthma

DAR Boldy, JG Ayres - Respiratory medicine, 1993 - Elsevier
We conducted a double-blind parallel-group study to compare the efficacy of inhaled
nedocromil sodium and inhaled sodium cromogylcate in patients aged 50 years or over with …

Inhibition of eosinophil density change and leukotriene C4 generation by nedocromil sodium

JB Sedgwick, U Bjornsdottir, KM Geiger… - Journal of allergy and …, 1992 - Elsevier
Nedocromil sodium (NS) has been shown to inhibit the late asthma response to inhaled
antigen and to control symptoms in chronic asthma; in both processes the eosinophil is …