Mitochondria are membrane organelles present in almost all eukaryotic cells. In addition to
their well-known role in energy production, mitochondria regulate central cellular processes …

Mitochondrial damage is implicated as a major contributing factor for a number of
noncommunicable chronic diseases such as cardiovascular diseases, cancer, obesity, and …

Humanin (HN) is a small mitochondrial-derived cytoprotective polypeptide encoded by
mtDNA. HN exhibits protective effects in several cell types, including leukocytes, germ cells …

Abnormal function of suborganelles such as mitochondria and endoplasmic reticulum often
leads to abnormal function of cardiomyocytes or vascular endothelial cells and …

Mitochondria provide energy to the cell during aerobic respiration by supplying~ 95% of the
adenosine triphosphate (ATP) molecules via oxidative phosphorylation. These organelles …

Mitochondrial dysfunction may play a crucial role in various diseases due to its roles in the
regulation of energy production and cellular metabolism. Serine/threonine kinase (AKT) is a …

Aging has been viewed both as a random process due to accumulation of molecular and
cellular damage over time and as a programmed process linked to cellular pathway …

Both obesity and gestational diabetes mellitus (GDM) lead to poor maternal and fetal
outcomes, including pregnancy complications, fetal growth issues, stillbirth, and …

Mitochondria are the main site of intracellular synthesis of ATP, which provides energy for
various physiological activities of the cell. Cardiomyocytes have a high density of …

Mitochondria are eukaryotic organelles known best for their roles in energy production and
metabolism. While often thought of as simply the 'powerhouse of the cell,'these organelles …