The emerging treatment landscape of targeted therapy in non-small-cell lung cancer
M Yuan, LL Huang, JH Chen, J Wu, Q Xu - Signal transduction and …, 2019 - nature.com
Lung cancer is one of the most common cancer in the world. In 2018, there were over 2
million new cases of lung cancer and over 1.7 million deaths were attributed to lung cancer …
million new cases of lung cancer and over 1.7 million deaths were attributed to lung cancer …
Preoperative and postoperative systemic therapy for operable non–small-cell lung cancer
Cisplatin-based adjuvant chemotherapy remains the standard of care for patients with
resected stage II or III non–small-cell lung cancer. However, biomarker-informed clinical …
resected stage II or III non–small-cell lung cancer. However, biomarker-informed clinical …
Current landscape of non-small cell lung cancer: epidemiology, histological classification, targeted therapies, and immunotherapy
O Rodak, MD Peris-Díaz, M Olbromski… - Cancers, 2021 - mdpi.com
Simple Summary The abundance and the dynamic of the studies on NSCLC require
frequent summaries of the current achievements in the field. In our review, we aimed to …
frequent summaries of the current achievements in the field. In our review, we aimed to …
Gefitinib versus vinorelbine plus cisplatin as adjuvant treatment for stage II–IIIA (N1–N2) EGFR-mutant NSCLC (ADJUVANT/CTONG1104): a randomised, open-label …
WZ Zhong, Q Wang, WM Mao, ST Xu, L Wu… - The Lancet …, 2018 - thelancet.com
Background Cisplatin-based adjuvant chemotherapy is the standard of care for patients with
resected stage II–IIIA non-small-cell lung cancer (NSCLC). RADIANT and SELECT trial data …
resected stage II–IIIA non-small-cell lung cancer (NSCLC). RADIANT and SELECT trial data …
Erlotinib Versus Gemcitabine Plus Cisplatin as Neoadjuvant Treatment of Stage IIIA-N2 EGFR-Mutant Non–Small-Cell Lung Cancer (EMERGING-CTONG 1103): A …
WZ Zhong, KN Chen, C Chen, CD Gu… - Journal of clinical …, 2019 - ascopubs.org
PURPOSE To assess the benefits of epidermal growth factor receptor (EGFR) tyrosine
kinase inhibitors as neoadjuvant/adjuvant therapies in locally advanced EGFR mutation …
kinase inhibitors as neoadjuvant/adjuvant therapies in locally advanced EGFR mutation …
Adjuvant erlotinib versus placebo in patients with stage IB-IIIA non–small-cell lung cancer (RADIANT): A randomized, double-blind, phase III trial
K Kelly, NK Altorki, WEE Eberhardt… - Journal of Clinical …, 2015 - ascopubs.org
Purpose Epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitors have proven
efficacy in advanced non–small-cell lung cancer (NSCLC). We hypothesized that erlotinib …
efficacy in advanced non–small-cell lung cancer (NSCLC). We hypothesized that erlotinib …
Management of non-small-cell lung cancer: recent developments
Non-small-cell lung cancer is one of the leading causes of deaths from cancer worldwide.
Therefore, improvements in diagnostics and treatments are urgently needed. In this review …
Therefore, improvements in diagnostics and treatments are urgently needed. In this review …
Role of chemotherapy and targeted therapy in early-stage non-small cell lung cancer
M Nagasaka, SM Gadgeel - Expert review of anticancer therapy, 2018 - Taylor & Francis
Introduction: Adjuvant platinum based chemotherapy is accepted as standard of care in
stage II and III non-small cell lung cancer (NSCLC) patients and is often considered in …
stage II and III non-small cell lung cancer (NSCLC) patients and is often considered in …
SELECT: a phase II trial of adjuvant erlotinib in patients with resected epidermal growth factor receptor–mutant non–small-cell lung cancer
NA Pennell, JW Neal, JE Chaft, CG Azzoli… - Journal of Clinical …, 2019 - ascopubs.org
Purpose Given the pivotal role of epidermal growth factor receptor (EGFR) inhibitors in
advanced EGFR-mutant non–small-cell lung cancer (NSCLC), we tested adjuvant erlotinib …
advanced EGFR-mutant non–small-cell lung cancer (NSCLC), we tested adjuvant erlotinib …
[HTML][HTML] Distinct clinical course of EGFR-mutant resected lung cancers: results of testing of 1118 surgical specimens and effects of adjuvant gefitinib and erlotinib
Background: EGFR and KRAS mutations are mutually exclusive and predict outcomes with
epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) treatment in patients …
epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) treatment in patients …