Targeted therapy for head and neck cancer: signaling pathways and clinical studies
Head and neck cancer (HNC) is malignant, genetically complex and difficult to treat and is
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …
[HTML][HTML] Therapeutic approaches for the treatment of head and neck squamous cell carcinoma–An update on clinical trials
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common non-skin
cancer with a tobacco consumption and infection with high-risk human papillomavirus (HPV) …
cancer with a tobacco consumption and infection with high-risk human papillomavirus (HPV) …
Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma
R Wilken, MS Veena, MB Wang, ES Srivatsan - Molecular cancer, 2011 - Springer
Curcumin (diferuloylmethane) is a polyphenol derived from the Curcuma longa plant,
commonly known as turmeric. Curcumin has been used extensively in Ayurvedic medicine …
commonly known as turmeric. Curcumin has been used extensively in Ayurvedic medicine …
Addition of bevacizumab to standard chemoradiation for locoregionally advanced nasopharyngeal carcinoma (RTOG 0615): a phase 2 multi-institutional trial
Background We aimed to improve the outcomes for locoregionally advanced
nasopharyngeal carcinoma by testing the feasibility and safety of the addition of …
nasopharyngeal carcinoma by testing the feasibility and safety of the addition of …
Clinical update on cancer: molecular oncology of head and neck cancer
Head and neck cancers encompass a heterogeneous group of tumours that, in general, are
biologically aggressive in nature. These cancers remain difficult to treat and treatment can …
biologically aggressive in nature. These cancers remain difficult to treat and treatment can …
Optical image-guided surgery—where do we stand?
S Keereweer, JDF Kerrebijn, PBAA Van Driel… - Molecular Imaging and …, 2011 - Springer
In cancer surgery, intra-operative assessment of the tumor-free margin, which is critical for
the prognosis of the patient, relies on the visual appearance and palpation of the tumor …
the prognosis of the patient, relies on the visual appearance and palpation of the tumor …
Biomarkers to predict the clinical efficacy of bevacizumab in cancer
Bevacizumab is a monoclonal antibody against vascular endothelial growth factor that has
antiangiogenic activity and improves progression-free survival in many solid malignancies …
antiangiogenic activity and improves progression-free survival in many solid malignancies …
[HTML][HTML] EPHB2 carried on small extracellular vesicles induces tumor angiogenesis via activation of ephrin reverse signaling
S Sato, S Vasaikar, A Eskaros, Y Kim, JS Lewis… - JCI insight, 2019 - ncbi.nlm.nih.gov
Angiogenesis is a key process that allows nutrient uptake and cellular trafficking and is
coopted in cancer to enable tumor growth and metastasis. Recently, extracellular vesicles …
coopted in cancer to enable tumor growth and metastasis. Recently, extracellular vesicles …
The VEGF pathway in cancer and disease: responses, resistance, and the path forward
Antiangiogenesis was proposed as a novel target for the treatment of cancer 40 years ago.
Since the original hypothesis put forward by Judah Folkman in 1971, factors that mediate …
Since the original hypothesis put forward by Judah Folkman in 1971, factors that mediate …
[HTML][HTML] Molecular pathology of lung cancer: key to personalized medicine
L Cheng, RE Alexander, GT MacLennan… - Modern Pathology, 2012 - Elsevier
The majority of lung adenocarcinoma patients with epidermal growth factor receptor-(EGFR)
mutated or EML4–ALK rearrangement-positive tumors are sensitive to tyrosine kinase …
mutated or EML4–ALK rearrangement-positive tumors are sensitive to tyrosine kinase …