Early detection of tumor cell death in glioblastoma following treatment with chemoradiation
has the potential to distinguish between true disease progression and pseudoprogression …

Advances in radiation technology, such as intensity-modulated radiation therapy (IMRT),
have largely enabled a biological dose escalation of the target volume (TV) and reduce the …

Although MR imaging (MRI) and MR spectroscopic imaging (MRSI) have been applied in
the diagnosis and treatment planning for brain tumors, their prognostic significance has not …

The vast majority of malignant gliomas relapse after surgery and standard radio-
chemotherapy. Novel molecular and cellular therapies are thus being developed, targeting …

Despite multimodal treatment, the prognosis of high-grade gliomas is grim. As tumor growth
is critically dependent on new blood vessel formation, antiangiogenic treatment approaches …

In addition to conventional magnetic resonance (MR) imaging techniques, advanced
techniques including diffusion-weighted (DW) imaging, proton nuclear magnetic resonance …

Hematogeneous spread of primary neoplasm can result in central nervous system (CNS)
disease burden in various anatomically distinct regions; calvarial, pachymeningeal …

Radiation therapy (RT) is a major treatment modality for malignant and benign brain tumors.
Concerns of radiation effects on the brain tissue and neurocognitive function and quality of …

We developed a technique that allows the routine integration of PET in stereotactic
neurosurgery, including radiosurgery. We report our clinical experience with the combined …

Management of patients with glioblastoma (GBM) is complex and involves implementing
standard therapies including resection, radiation therapy, and chemotherapy, as well as …