Antibacterial resistance is one of the greatest threats to human health. The development of
new therapeutics against bacterial pathogens has slowed drastically since the approvals of …

Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

Bacterial membrane barrier provides a cytoplasmic environment for organelles of bacteria.
The membrane is composed of lipid compounds containing phosphatide protein and a …

Many serious infections result from persistent microbial biofilms that do not respond to
conventional antibiotic therapy. Various therapeutic approaches have been developed and …

The Pseudomonas aeruginosa LasB elastase (elastase B, pseudolysin) is the predominant
protease in the P. aeruginosa secretome. It has been shown to hydrolyse a vast array of host …

Infections with Pseudomonas aeruginosa have been marked with the highest priority for
surveillance and epidemiological research on the basis of parameters such as incidence …

Recent efforts in biological engineering have made detection of nucleic acids in samples
more rapid, inexpensive and sensitive using CRISPR-based approaches. We expand one of …

Pseudomonas aeruginosa is a Gram-negative bacterium causing diseases in plants,
animals, and humans, and its drug resistance is a major concern in medical care. Biofilms …

Infections caused by multidrug-resistant (MDR) bacteria are increasing worldwide, and with
limited clinically available antibiotics, it is urgent to develop new antimicrobials to combat …

Development of new bacterial biofilm inhibitors as antibacterial synergists is an effective
strategy to solve the resistance of Pseudomonas aeruginosa. In this paper, a series of 3 …