[HTML][HTML] Combining crocin and sorafenib improves their tumor-inhibiting effects in a rat model of diethylnitrosamine-induced cirrhotic-hepatocellular carcinoma
Simple Summary Liver cancer represents one of the most lethal forms of cancer, with
hepatocellular carcinoma (HCC) accounting for the majority of its incidences and deaths …
hepatocellular carcinoma (HCC) accounting for the majority of its incidences and deaths …
[HTML][HTML] Therapeutic effects of crocin alone or in combination with sorafenib against hepatocellular carcinoma: in vivo & in vitro insights
This study investigated the therapeutic effects of the phytochemical crocin alone or in
combination with sorafenib both in rats chemically induced with hepatocellular carcinoma …
combination with sorafenib both in rats chemically induced with hepatocellular carcinoma …
Xanthosine, a purine glycoside mediates hepatic glucose homeostasis through inhibition of gluconeogenesis and activation of glycogenesis via regulating the AMPK …
Abstract Type 2 Diabetes Mellitus (T2DM) is characterized by hepatic insulin resistance,
which results in increased glucose production and reduced glycogen storage in the liver …
which results in increased glucose production and reduced glycogen storage in the liver …
[HTML][HTML] Advances in neovascularization after diabetic ischemia
Y Cai, GY Zang, Y Huang, Z Sun, LL Zhang… - World Journal of …, 2022 - ncbi.nlm.nih.gov
With the high incidence of diabetes around the world, ischemic complications cause a
serious influence on people's production and living. Neovascularization plays a significant …
serious influence on people's production and living. Neovascularization plays a significant …
Exploring in vitro modeling in hepatocarcinogenesis research: morphological and molecular features and similarities to the corresponding human disease
LC Valente, GP Bacil, L Riechelmann-Casarin… - Life Sciences, 2024 - Elsevier
The hepatocellular carcinoma (HCC) features a remarkable epidemiological burden,
ranking as the third most lethal cancer worldwide. As the HCC-related molecular and …
ranking as the third most lethal cancer worldwide. As the HCC-related molecular and …
Protective role of hesperetin in sorafenib-induced hepato-and neurotoxicity in mice via modulating apoptotic pathways and mitochondrial reprogramming
D Zaafar, HMA Khalil, R Elnaggar, DZ Saad… - Life Sciences, 2024 - Elsevier
Introduction Sorafenib, an FDA-approved standard chemotherapy for advanced
hepatocellular carcinoma, is associated with numerous adverse effects that significantly …
hepatocellular carcinoma, is associated with numerous adverse effects that significantly …
Baicalein ameliorates polymyxin B-induced acute renal injury by inhibiting ferroptosis via regulation of SIRT1/p53 acetylation
M Yu, H Li, B Wang, Z Wu, S Wu, G Jiang… - Chemico-Biological …, 2023 - Elsevier
The polypeptide antibiotic Polymyxin B (PMB) can cause acute kidney injury (AKI), we found
that ferroptosis is one of the main mechanisms of renal injury caused by PMB. It was …
that ferroptosis is one of the main mechanisms of renal injury caused by PMB. It was …
COX-2 inhibition mediated aggregation-induced emission photosensitizer target the Golgi apparatus for selective imaging of cancer cells and enhanced …
X Wang, X Wang, Y Li, Z Qi - Dyes and Pigments, 2024 - Elsevier
Photodynamic therapy (PDT) exerts its therapeutic effects by inducing apoptosis, necrosis,
and microvascular damage in tumor cells, but it also causes inflammation and induces the …
and microvascular damage in tumor cells, but it also causes inflammation and induces the …
Protective effect of San Huang Pill and its bioactive compounds against ulcerative colitis in Drosophila via modulation of JAK/STAT, apoptosis, Toll, and Nrf2/Keap1 …
B Li, M Xiu, L He, S Zhou, S Yi, X Wang, W Cao… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance San Huang Pill (SHP) is a prescription in
Dunhuang Ancient Medical Prescription, which has the efficacy of heat-clearing and …
Dunhuang Ancient Medical Prescription, which has the efficacy of heat-clearing and …
Isolation and characterization of bioactive components from hydroalcoholic extract of Cymbopogon jwarancusa (Jones) Schult. to evaluate its hepatoprotective activity
S Sumaiya, A Siddiqui, SS Chaudhary, M Aslam… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Cymbopogon jwarancusa (Jones) Schult.(Family:
Poacea/Gramineae) is being used to treat numerous ailments in traditional/folklore and …
Poacea/Gramineae) is being used to treat numerous ailments in traditional/folklore and …