Biology, risk stratification, and therapy of pediatric acute leukemias: an update
CH Pui, WL Carroll, S Meshinchi… - Journal of clinical …, 2011 - ascopubs.org
Purpose We review recent advances in the biologic understanding and treatment of
childhood acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML), identify …
childhood acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML), identify …
Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel
U Creutzig, MM van Den Heuvel-Eibrink… - Blood, The Journal …, 2012 - ashpublications.org
Despite major improvements in outcome over the past decades, acute myeloid leukemia
(AML) remains a life-threatening malignancy in children, with current survival rates of∼ …
(AML) remains a life-threatening malignancy in children, with current survival rates of∼ …
Improved outcome in pediatric relapsed acute myeloid leukemia: results of a randomized trial on liposomal daunorubicin by the International BFM Study Group
GJL Kaspers, M Zimmermann, D Reinhardt… - Journal of Clinical …, 2013 - ascopubs.org
Purpose In pediatric relapsed acute myeloid leukemia (AML), optimal reinduction therapy is
unknown. Studies suggest that liposomal daunorubicin (DNX; DaunoXome; Galen …
unknown. Studies suggest that liposomal daunorubicin (DNX; DaunoXome; Galen …
Acute myeloid leukemia
JE Rubnitz, B Gibson, FO Smith - Pediatric clinics of North America, 2008 - Elsevier
Acute myeloid leukemia (AML) is a heterogeneous group of leukemias that result from clonal
transformation of hematopoietic precursors through the acquisition of chromosomal …
transformation of hematopoietic precursors through the acquisition of chromosomal …
Relapse after allogeneic stem cell transplantation
AJ Barrett, M Battiwalla - Expert review of hematology, 2010 - Taylor & Francis
Since allogeneic stem cell transplantation (SCT) represents an intensive curative treatment
for high-risk malignancies, its failure to prevent relapse leaves few options for successful …
for high-risk malignancies, its failure to prevent relapse leaves few options for successful …
Risk-stratified therapy and the intensive use of cytarabine improves the outcome in childhood acute myeloid leukemia: the AML99 trial from the Japanese Childhood …
I Tsukimoto, A Tawa, K Horibe, K Tabuchi… - Journal of Clinical …, 2009 - ascopubs.org
Purpose To improve the prognosis in children with newly diagnosed acute myeloid leukemia
(AML) by introducing a dose-dense intensive chemotherapy regimen and an appropriate …
(AML) by introducing a dose-dense intensive chemotherapy regimen and an appropriate …
Consequent and intensified relapse therapy improved survival in pediatric AML: results of relapse treatment in 379 patients of three consecutive AML-BFM trials
A Sander, M Zimmermann, M Dworzak, G Fleischhack… - Leukemia, 2010 - nature.com
Relapse remains the major cause of treatment failure in pediatric acute myeloid leukemia
(AML). We analyzed the clinical characteristics, treatment response to relapse treatment and …
(AML). We analyzed the clinical characteristics, treatment response to relapse treatment and …
Decitabine and vorinostat with FLAG chemotherapy in pediatric relapsed/refractory AML: Report from the therapeutic advances in childhood leukemia and lymphoma …
L Pommert, ES Schafer, J Malvar… - American journal of …, 2022 - Wiley Online Library
Survival outcomes for relapsed/refractory pediatric acute myeloid leukemia (R/R AML)
remain dismal. Epigenetic changes can result in gene expression alterations which are …
remain dismal. Epigenetic changes can result in gene expression alterations which are …
Acute myeloid leukemia in children: Current status and future directions
T Taga, D Tomizawa, H Takahashi… - Pediatrics …, 2016 - Wiley Online Library
Acute myeloid leukemia (AML) accounts for 25% of pediatric leukemia and affects
approximately 180 patients annually in Japan. The treatment outcome for pediatric AML has …
approximately 180 patients annually in Japan. The treatment outcome for pediatric AML has …
Survival following relapse in children with acute myeloid leukemia: a report from AML-BFM and COG
M Rasche, M Zimmermann, E Steidel, T Alonzo… - Cancers, 2021 - mdpi.com
Simple Summary Acute myeloid leukemia in children remains a difficult disease to cure
despite intensive therapies that push the limits of tolerability. Though the intent of initial …
despite intensive therapies that push the limits of tolerability. Though the intent of initial …