Despite much recent progress, prostate cancer continues to represent a major cause of
cancer-related mortality and morbidity in men. Since early studies on the role of the …

Various preclinical models have been developed to clarify the pathophysiology of prostate
cancer (PCa). Traditional PCa cell lines from clinical metastatic lesions, as exemplified by …

The Cellosaurus is a knowledge resource on cell lines. It aims to describe all cell lines used
in biomedical research. Its scope encompasses both vertebrates and invertebrates …

New incidence of prostate cancer is a major public health issue in the Western world, and
has been rising in other areas of the globe in recent years. In an effort to understanding the …

Purpose: Prostate cancer translational research has been hampered by the lack of
comprehensive and tractable models that represent the genomic landscape of clinical …

Androgen receptor (AR) antagonists, such as enzalutamide, have had a major impact on the
treatment of metastatic castration-resistant prostate cancer (CRPC). However, even with the …

A common stage of advanced prostate cancer is castration-resistant prostate cancer
(CRPC), greater understanding of which is required in order to address and solve the …

Metastatic progression of advanced prostate cancer is a major clinical problem. Identifying
the cell (s) of origin in prostate cancer and its distant metastases may permit the …

Prostate cancers are largely unresponsive to immune checkpoint inhibitors (ICIs), and there
is strong evidence that programmed death-ligand 1 (PD-L1) expression itself must be …

This communication reports that three prostate cancer cells of differing metastatic potential
were discriminated based on their Young's moduli (LNCaP–287±52 N m− 2, PC-3 …