Steatotic liver disease: metabolic dysfunction, alcohol, or both?

K Staufer, RE Stauber - Biomedicines, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) and alcohol-related liver disease (ALD), both of
them accounting for fatty liver disease (FLD), are among the most common chronic liver …

Alcohol, the gut microbiome, and liver disease

MH Jew, CL Hsu - Journal of Gastroenterology and Hepatology, 2023 - Wiley Online Library
The microorganisms inhabiting our gastrointestinal tract are critical for human health.
Chronic heavy alcohol use can modulate the composition and function of the gut microbiota …

Sex-and estrous-related response patterns for alcohol depend critically on the level of compulsion-like challenge

TDO Sergio, D Darevsky, J Kellner… - Progress in Neuro …, 2024 - Elsevier
Alcohol use disorder is a substantial social and economic burden. During the last years, the
number of women with drinking problems has been increasing, and one main concern is …

Folic acid protects against ethanol-induced hepatic mitophagy imbalance by ROS scavenging and attenuating the elevated Hcy levels

H Zhao, H Gao, Y Zhang, T Lan, J Wang… - Journal of Agricultural …, 2023 - ACS Publications
Ample evidence indicates that ethanol-induced oxidative stress and mitochondrial
dysfunction are central to the pathogenesis of alcoholic liver disease (ALD). As an adaptive …

[HTML][HTML] Animal models of compulsion alcohol drinking: Why we love quinine-resistant intake and what we learned from it

T De Oliveira Sergio, RM Frasier, FW Hopf - Frontiers in Psychiatry, 2023 - frontiersin.org
Alcohol Use Disorder (AUD) ranks among the most prevalent mental disorders, extracting~
$250 billion/year in the US alone and producing myriad medical and social harms. Also, the …

Sex differences in heart rate variability measures that predict alcohol drinking in rats

RM Frasier, PA Starski, T de Oliveira Sergio… - Addiction …, 2024 - Wiley Online Library
Problem alcohol drinking continues to be a substantial cost and burden. In addition, alcohol
consumption in women has increased in recent decades, and women can have greater …

Bibliometric study of immunotherapy for hepatocellular carcinoma

Z Li, Y Zhang, B Zhang, R Guo, M He, ZL Liu… - Frontiers in …, 2023 - frontiersin.org
Background Hepatocellular carcinoma (HCC), recognized as a significant global health
concern, ranks as the sixth most prevalent form of cancer and is the third leading cause of …

Hepatoprotective effects of biochanin a on thioacetamide-induced liver cirrhosis in experimental rats

MY Ibrahim, ZZ Alamri, ASM Juma, SA Hamood… - Molecules, 2023 - mdpi.com
The protective effect of biochanin A (BCA) on the histopathology, immunohistochemistry,
and biochemistry of thioacetamide (TAA)-induced liver cirrhosis in vivo was investigated …

Raman scattering-based optical sensing of chronic liver diseases

K Alkhuder - Photodiagnosis and Photodynamic Therapy, 2023 - Elsevier
Chronic liver diseases (CLDs) are a major public health problem. Despite the progress
achieved in fighting against viral hepatitis, the emergence of non-alcoholic fatty liver disease …

Hepatic protein tyrosine phosphatase Shp2 disruption mitigates the adverse effects of ethanol in the liver by modulating oxidative stress and ERK signaling

MF Hsu, G LeBleu, L Flores, A Parkhurst, LE Nagy… - Life Sciences, 2024 - Elsevier
Aims Chronic excessive alcohol intake is a significant cause of alcohol-associated liver
disease (ALD), a leading contributor to liver-related morbidity and mortality. The Src …