[HTML][HTML] Glucose-regulated proteins in cancer: molecular mechanisms and therapeutic potential
AS Lee - Nature Reviews Cancer, 2014 - nature.com
The glucose-regulated proteins (GRPs) are stress-inducible chaperones that mostly reside
in the endoplasmic reticulum or the mitochondria. Recent advances show that the GRPs …
in the endoplasmic reticulum or the mitochondria. Recent advances show that the GRPs …
[HTML][HTML] GRP78 at the centre of the stage in cancer and neuroprotection
C Casas - Frontiers in neuroscience, 2017 - frontiersin.org
The 78-kDa glucose-regulated protein GRP78, also known as BiP and HSP5a, is a
multifunctional protein with activities far beyond its well-known role in the unfolded protein …
multifunctional protein with activities far beyond its well-known role in the unfolded protein …
Involvement of members of the cadherin superfamily in cancer
G Berx, F Van Roy - Cold Spring Harbor perspectives in …, 2009 - cshperspectives.cshlp.org
We review the role of cadherins and cadherin-related proteins in human cancer. Cellular
and animal models for human cancer are also dealt with whenever appropriate. E-cadherin …
and animal models for human cancer are also dealt with whenever appropriate. E-cadherin …
Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting
M Ni, Y Zhang, AS Lee - Biochemical Journal, 2011 - portlandpress.com
GRP78 (glucose-regulated protein of 78 kDa) is traditionally regarded as a major ER
(endoplasmic reticulum) chaperone facilitating protein folding and assembly, protein quality …
(endoplasmic reticulum) chaperone facilitating protein folding and assembly, protein quality …
Role of the unfolded protein response regulator GRP78/BiP in development, cancer, and neurological disorders
M Wang, S Wey, Y Zhang, R Ye… - Antioxidants & redox …, 2009 - liebertpub.com
GRP78/BiP is a major endoplasmic reticulum (ER) chaperone protein critical for protein
quality control of the ER, as well as controlling the activation of the ER-transmembrane …
quality control of the ER, as well as controlling the activation of the ER-transmembrane …
[HTML][HTML] Endoplasmic reticulum stress and homeostasis in reproductive physiology and pathology
The endoplasmic reticulum (ER), comprises 60% of the total cell membrane and interacts
directly or indirectly with several cell organelles ie, Golgi bodies, mitochondria and …
directly or indirectly with several cell organelles ie, Golgi bodies, mitochondria and …
[HTML][HTML] Cell surface relocalization of the endoplasmic reticulum chaperone and unfolded protein response regulator GRP78/BiP
The recent discovery that GRP78/BiP, a typical endoplasmic reticulum (ER) lumenal
chaperone, can be expressed on the cell surface, interacting with an increasing repertoire of …
chaperone, can be expressed on the cell surface, interacting with an increasing repertoire of …
Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies
A genome-wide association (GWA) study with pooled DNA in adult attention-
deficit/hyperactivity disorder (ADHD) employing~ 500K SNP markers identifies novel risk …
deficit/hyperactivity disorder (ADHD) employing~ 500K SNP markers identifies novel risk …
Glucose‐regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders
The 78 kDa glucose‐regulated protein (GRP78) is an endoplasmic reticulum (ER)‐resident
molecular chaperone. GRP78 is a member of the 70 kDa heat shock family of proteins …
molecular chaperone. GRP78 is a member of the 70 kDa heat shock family of proteins …
GRP78 is an important host factor for Japanese encephalitis virus entry and replication in mammalian cells
M Nain, S Mukherjee, SP Karmakar, AW Paton… - Journal of …, 2017 - Am Soc Microbiol
Japanese encephalitis virus (JEV), a mosquito-borne flavivirus, is the leading cause of viral
encephalitis in Southeast Asia with potential to become a global pathogen. Here, we identify …
encephalitis in Southeast Asia with potential to become a global pathogen. Here, we identify …