Methylation of cytosine bases in DNA provides a layer of epigenetic control in many
eukaryotes that has important implications for normal biology and disease. Therefore …

The human disease methylation database (DiseaseMeth, http://bioinfo. hrbmu. edu.
cn/diseasemeth/) is an interactive database that aims to present the most complete …

Epigenetics refers to stable and long-term alterations of cellular traits that are not caused by
changes in the DNA sequence per se. Rather, covalent modifications of DNA and histones …

Predominantly occurring on cytosine, DNA methylation is a process by which cells can
modify their DNAs to change the expression of gene products. It plays very important roles in …

Long-noncoding RNAs (lncRNAs) have been shown to participate in sensitizing or de-
sensitizing cancer cells to chemical drugs during cancer therapeutics. Notably, a plethora of …

Epigenetics, and more specifically DNA methylation is a fast evolving research area. In
almost every cancer type, each month new publications confirm the differentiated regulation …

Cancer is ranked as one of the top killers in all human diseases and continues to have a
devastating effect on the population around the globe. Current research efforts are aiming to …

Covalent DNA modifications, such as 5-methylcytosine (5mC), are increasingly the focus of
numerous research programs. In eukaryotes, both 5mC and 5-hydroxymethylcytosine …

DNA methylation is an important mode of regulation in epigenetic mechanisms, and it is one
of the research foci in the field of epigenetics. DNA methylation modification affects a series …

Introduction: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a key glycolytic
enzyme, but recent studies have shown its non-glycolytic role in cell death, survival …