[HTML][HTML] Recent advances in GelMA hydrogel transplantation for musculoskeletal disorders and related disease treatment

B Lv, L Lu, L Hu, P Cheng, Y Hu, X Xie, G Dai, B Mi… - Theranostics, 2023 - ncbi.nlm.nih.gov
Increasing data reveals that gelatin that has been methacrylated is involved in a variety of
physiologic processes that are important for therapeutic interventions. Gelatin methacryloyl …

Living microecological hydrogels for wound healing

G Chen, F Wang, X Zhang, Y Shang, Y Zhao - Science Advances, 2023 - science.org
Chronic hard-to-heal wounds draw great attention worldwide, as their treatments are limited
by infections and hypoxia. Inspired by the natural oxygen production capacity of algae and …

An autocatalytic multicomponent DNAzyme nanomachine for tumor-specific photothermal therapy sensitization in pancreatic cancer

J Yan, X Ma, D Liang, M Ran, D Zheng, X Chen… - Nature …, 2023 - nature.com
Multicomponent deoxyribozymes (MNAzymes) have great potential in gene therapy, but
their ability to recognize disease tissue and further achieve synergistic gene regulation has …

A versatile GelMA composite hydrogel: Designing principles, delivery forms and biomedical applications

Y Zhang, J Lv, J Zhao, G Ling, P Zhang - European Polymer Journal, 2023 - Elsevier
Gelatin methacryloyl (GelMA), a kind of modified biomaterials with adjustable degradability
from gelatin, can composite with various composite materials and therapeutic substances …

Nanoarchitectonics of cartilage-targeting hydrogel microspheres with reactive oxygen species responsiveness for the repair of osteoarthritis

H Yu, C Huang, X Kong, J Ma, P Ren… - … Applied Materials & …, 2022 - ACS Publications
Clinically, intra-articular administration can hardly achieve the truly targeted therapy, and the
drugs are usually insufficient to show local and long-term therapeutic effects because of their …

Biologics‐loaded photothermally dissolvable hyaluronic acid microneedle patch for psoriasis treatment

D Wu, X Shou, Y Yu, X Wang, G Chen… - Advanced Functional …, 2022 - Wiley Online Library
Emerging biologics, such as monoclonal antibodies (mAbs), are the most promising
treatment for psoriasis, while their effective delivery to the local inflammatory area of the skin …

Flower‐like nanozymes with large accessibility of single atom catalysis sites for ROS generation boosted tumor therapy

Y Xing, L Wang, L Wang, J Huang… - Advanced Functional …, 2022 - Wiley Online Library
The use of reactive oxygen species (ROS) generators based on single‐atom catalysts
(SACs) has been an emerging strategy for mediating tumor therapy, however, the current …

Minimally invasive injection of biomimetic Nano@ Microgel for in situ ovarian cancer treatment through enhanced photodynamic reactions and photothermal …

X Ma, W Zhou, R Zhang, C Zhang, J Yan, J Feng… - Materials Today Bio, 2023 - Elsevier
Photodynamic therapy (PDT) induces immunogenic cell death (ICD) by producing reactive
oxygen species (ROS), making it an ideal method for cancer treatment. However, the …

A multifunctional nanoaggregate‐based system for detection of rheumatoid arthritis via optoacoustic/NIR‐II fluorescent imaging and therapy via inhibiting JAK‐STAT …

J Chen, L Chen, Z She, F Zeng, S Wu - Aggregate, 2024 - Wiley Online Library
Rheumatoid arthritis (RA) is a debilitating autoimmune disease that causes chronic pain and
serious complications, presenting a significant challenge to treat. Promising approaches for …

Microfluidic generation of helical micromotors for muscle tissue engineering

W Zhuge, X Ding, W Zhang, D Zhang, H Wang… - Chemical Engineering …, 2022 - Elsevier
Building units play an important and critical role in muscle tissue engineering, which has
aroused increasing attention in recent decades. The current muscle units are suffering from …