Sequencing of the 16S rRNA gene (16S) has long been a go-to method for microbiome
characterization due to its accessibility and lower cost compared to shotgun metagenomic …

Bats provide important ecosystem services as pollinators, seed dispersers, and/or insect
controllers, but they have also been found harboring different viruses with zoonotic potential …

Background: Respiratory viruses significantly impact global morbidity and mortality, causing
more disease in humans than any other infectious agent. Beyond pathogens, various …

The influence of living in small remote villages on the diversity of viruses in the nasal
mucosa was investigated in three Colombian villages with very different levels of geographic …

Introduction Metagenomics is increasingly considered for clinical diagnostics. In order for
this technology to become integrated in the clinical microbiology laboratory, process controls …

Background Recently, metagenomic next-generation sequencing (mNGS) has been used in
the diagnosis of infectious diseases (IDs) as an emerging and powerful tool. However …

This is a comprehensive guide to single-stranded RNA phages (family Leviviridae), first
discovered in 1961. These phages played a unique role in early studies of molecular …

Emerging infectious disease threats require rapid response tools to inform diagnostics,
treatment, and outbreak control. RNA-based metagenomics offers this; however, most …

Background High-throughput sequencing (HTS) technologies completed by the
bioinformatic analysis of the generated data are becoming an important detection technique …

Acute respiratory failure (ARF) is common in hematological malignancies patients, notably
those with acute leukemia, myelodysplastic syndrome, or allogeneic stem-cell …