Cancer nanomedicine based on polyethylenimine-mediated multifunctional nanosystems

J Li, X Yu, X Shi, M Shen - Progress in Materials Science, 2022 - Elsevier
Owing to the unique structural characteristics and abundant amine groups, polyethylenimine
(PEI) plays a remarkable role in the construction of multifunctional nanosystems for versatile …

Preoperative detection and intraoperative visualization of brain tumors for more precise surgery: A new dual‐modality MRI and NIR nanoprobe

C Li, L Cao, Y Zhang, P Yi, M Wang, B Tan, Z Deng… - small, 2015 - Wiley Online Library
In clinical practice, it is difficult to identify tumor margins during brain surgery due to its
inherent infiltrative character. Herein, a unique dual‐modality nanoprobe (Gd‐DOTA‐Ag2S …

Drug delivery strategies to enhance the permeability of the blood–brain barrier for treatment of glioma

F Zhang, CL Xu, CM Liu - Drug Design, Development and Therapy, 2015 - Taylor & Francis
Gliomas are amongst the most insidious and destructive types of brain cancer and are
associated with a poor prognosis, frequent recurrences, and extremely high lethality despite …

Hybrid upconversion nanomaterials for optogenetic neuronal control

S Shah, JJ Liu, N Pasquale, J Lai, H McGowan… - Nanoscale, 2015 - pubs.rsc.org
Nanotechnology-based approaches offer the chemical control required to develop precision
tools suitable for applications in neuroscience. We report a novel approach employing …

Radiation-/hypoxia-induced solid tumor metastasis and regrowth inhibited by hypoxia-specific upconversion nanoradiosensitizer

Y Liu, Y Liu, W Bu, Q Xiao, Y Sun, K Zhao, W Fan, J Liu… - Biomaterials, 2015 - Elsevier
Tumor resistance to ionizing irradiation and cancer cell's metastasis stimulated by radiation
often lead to anti-cancer failure, and can be negatively caused by a key role–cellular …

Development of an inner filter effects-based upconversion nanoparticles–curcumin nanosystem for the sensitive sensing of fluoride ion

Y Liu, Q Ouyang, H Li, Z Zhang… - ACS applied materials & …, 2017 - ACS Publications
This paper describes a novel ratiometric fluorescence-based sensor for the detection of
fluoride ion. Yb3+, Er3+, and Tm3+ codoped NaYF4 upconversion nanoparticles (UCNPs) …

Emerging strategies to fabricate polymeric nanocarriers for enhanced drug delivery across blood-brain barrier: An overview

YH Song, R De, KT Lee - Advances in Colloid and Interface Science, 2023 - Elsevier
Blood-brain barrier (BBB) serves as an essential interface between central nervous system
(CNS) and its periphery, allowing selective permeation of ions, gaseous molecules, and …

Dual-targeted nanomedicines for enhanced tumor treatment

Y Zhu, J Feijen, Z Zhong - Nano Today, 2018 - Elsevier
Based on the overexpression of specific receptors on tumor cells, active targeting
nanomedicines have been developed with the ability to efficiently deliver imaging agents in …

Upconversion processes: versatile biological applications and biosafety

A Gulzar, J Xu, P Yang, F He, L Xu - Nanoscale, 2017 - pubs.rsc.org
Lanthanide-doped photon upconverting nanomaterials are evolving as a new class of
imaging contrast agents, offering highly promising prospects in the area of biomedical …

Drug/dye-loaded, multifunctional PEG–chitosan–iron oxide nanocomposites for methotraxate synergistically self-targeted cancer therapy and dual model imaging

J Lin, Y Li, Y Li, H Wu, F Yu, S Zhou, L Xie… - … applied materials & …, 2015 - ACS Publications
Multifunctional nanocomposites hold great potential to integrate therapeutic and diagnostic
functions into a single nanoscale structure. In this paper, we prepared the MTX-PEG-CS …