Epigenetic modifications in DNA bases and histone proteins play important roles in the
regulation of gene expression and genome stability. Chemical modification of DNA base …

Whole genome metagenomic sequencing is a powerful platform enabling the simultaneous
identification of all genes from entirely different kingdoms of organisms in a complex sample …

The emergence of canine parvovirus (CPV) represents a well-documented example
highlighting the emergence of a new virus through cross-species transmission. CPV …

Metagenomic high-throughput sequencing (mHTS) is a hypothesis-free, universal pathogen
detection technique for determination of the DNA/RNA sequences in a variety of sample …

The AID/APOBEC family enzymes convert cytosines in single-stranded DNA to uracils,
causing base substitutions and strand breaks. They are induced by cytokines produced …

The apolipoprotein B messenger RNA-editing, enzyme-catalytic, polypeptide-like 3
(APOBEC3) family of cytidine deaminases plays an important role in the innate immune …

Virus-host biological interaction is a continuous coevolutionary process involving both host
immune system and viral escape mechanisms. Flaviviridae family is composed of fast …

Members of the family Iridoviridae, collectively referred to as iridovirids, are large, double-
stranded DNA-containing viruses that infect invertebrates and cold-blooded (ectothermic) …

DNA methylation is involved in a diversity of processes in bacteria, including maintenance of
genome integrity and regulation of gene expression. Here, using Caulobacter crescentus as …

Three types of DNA methyl modifications have been detected in bacterial genomes, and
mechanistic studies have demonstrated roles for DNA methylation in physiological functions …