N-glycosylation is one of the most common types of protein modifications and it plays a vital
role in normal physiological processes. However, aberrant N-glycan modifications are …

CD14 is a co-receptor of Toll-like receptor (TLR)-4, with a critical role in innate immune
responses. CD14 recognizes bacterial lipopolysaccharides, pathogen-, and damage …

Coronary artery disease (CAD) is the most common cardiovascular disease (CVD), and
previous studies have shown a significant association between N-glycosylation, a highly …

Galectins are carbohydrate-binding proteins that regulate many cellular functions including
proliferation, adhesion, migration, and phagocytosis. Increasing experimental and clinical …

The efficacy of cancer therapies is limited to a great extent by immunosuppressive
mechanisms within the tumor microenvironment (TME). Numerous immune escape …

Protein glycosylation is a widespread posttranslational modification that can impact the
function of proteins. Dysregulated protein glycosylation has been linked to several diseases …

This study examines the intricate relationship between protein glycosylation dynamics and
therapeutic responses in Luminal A and Luminal B breast cancer subtypes, focusing on …

Atrial fibrillation is a disease with a complex pathophysiology, whose occurrence and
persistence are caused not only by aberrant electrical signaling in the heart, but by the …

After tissue damage, a series of molecular and cellular events are initiated to promote tissue
repair and regeneration to restore its original structure and function. These events include …

Crohn's disease (CD) is a chronic inflammation of the digestive tract that significantly impairs
patients' quality of life and well-being. Anti-TNF biologicals revolutionised the treatment of …