RNA packaging into extracellular vesicles: An orchestra of RNA‐binding proteins?

F Fabbiano, J Corsi, E Gurrieri… - Journal of …, 2020 - Wiley Online Library
Extracellular vesicles (EVs) are heterogeneous membranous particles released from the
cells through different biogenetic and secretory mechanisms. We now conceive EVs as …

[HTML][HTML] Cold shock proteins: from cellular mechanisms to pathophysiology and disease

JA Lindquist, PR Mertens - Cell Communication and Signaling, 2018 - Springer
Cold shock proteins are multifunctional RNA/DNA binding proteins, characterized by the
presence of one or more cold shock domains. In humans, the best characterized members of …

[HTML][HTML] A novel long noncoding RNA HOXC-AS3 mediates tumorigenesis of gastric cancer by binding to YBX1

E Zhang, X He, C Zhang, J Su, X Lu, X Si, J Chen… - Genome biology, 2018 - Springer
Background Recently, increasing evidence shows that long noncoding RNAs (lncRNAs)
play a significant role in human tumorigenesis. However, the function of lncRNAs in human …

[HTML][HTML] Multiomic analysis of the UV-induced DNA damage response

S Boeing, L Williamson, V Encheva, I Gori… - Cell reports, 2016 - cell.com
In order to facilitate the identification of factors and pathways in the cellular response to UV-
induced DNA damage, several descriptive proteomic screens and a functional genomics …

[HTML][HTML] Long non-coding RNAs in gastric cancer: New emerging biological functions and therapeutic implications

H Tan, S Zhang, J Zhang, L Zhu, Y Chen, H Yang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Gastric cancer (GC) is currently the fourth most common malignancy and the third leading
cause of cancer-related deaths worldwide. Long non-coding RNAs (lncRNAs) …

Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer

A Diaz-Lagares, AB Crujeiras… - Proceedings of the …, 2016 - National Acad Sciences
Long noncoding RNAs (lncRNAs) are important regulators of cellular homeostasis.
However, their contribution to the cancer phenotype still needs to be established. Herein, we …

Prostaglandin E2 and the EP receptors in malignancy: possible therapeutic targets?

G O'callaghan, A Houston - British journal of pharmacology, 2015 - Wiley Online Library
Elevated expression of COX‐2 and increased levels of PGE2 are found in numerous
cancers and are associated with tumour development and progression. Although …

Copy number amplification and SP1-activated lncRNA MELTF-AS1 regulates tumorigenesis by driving phase separation of YBX1 to activate ANXA8 in non-small cell …

X Lu, J Wang, W Wang, C Lu, T Qu, X He, X Liu, R Guo… - Oncogene, 2022 - nature.com
Long non-coding RNAs (lncRNAs) are reported to play key roles in tumorigenesis. However,
the mechanisms underlying lncRNA-mediated regulation of RNA-binding protein phase …

[HTML][HTML] A novel ten-gene signature predicting prognosis in hepatocellular carcinoma

T Zhou, Z Cai, N Ma, W Xie, C Gao, M Huang… - Frontiers in cell and …, 2020 - frontiersin.org
Hepatocellular carcinoma (HCC) has a dismal long-term outcome. We aimed to construct a
multi-gene model for prognosis prediction to inform HCC management. The cancer-specific …

Oncogenic Y‐box binding protein‐1 as an effective therapeutic target in drug‐resistant cancer

M Kuwano, T Shibata, K Watari, M Ono - Cancer science, 2019 - Wiley Online Library
Y‐box binding protein‐1 (YBX 1), a multifunctional oncoprotein containing an evolutionarily
conserved cold shock domain, dysregulates a wide range of genes involved in cell …