Abstract RNA-sequencing (RNA-seq) has a wide variety of applications, but no single
analysis pipeline can be used in all cases. We review all of the major steps in RNA-seq data …

Recent advances in high-throughput technologies have led to the emergence of systems
biology as a holistic science to achieve more precise modeling of complex diseases. Many …

Integrated-omics approaches are quickly spreading across microbiology research labs,
leading to (i) the possibility of detecting previously hidden features of microbial cells like …

Single cell high throughput genomic measurements are revolutionizing the fields of biology
and medicine, providing a means to tackle biological problems that have thus far been …

A main goal of Precision Medicine is that of incorporating and integrating the vast corpora on
different databases about the molecular and environmental origins of disease, into analytic …

Extracellular vesicles (EVs) are membranous structures derived from the endosomal system
or generated by plasma membrane shedding. Due to their composition of DNA, RNA …

Background Over the last decade network enrichment analysis has become popular in
computational systems biology to elucidate aberrant network modules. Traditionally, these …

JC polyomavirus (JCPyV) is a small non-enveloped virus that establishes lifelong, persistent
infection in most of the adult population. Immune-competent patients are generally …

Introduction: Multi-omic approaches are promising a broader view on cellular processes and
a deeper understanding of biological systems. with strongly improved high-throughput …

生物和非生物胁迫对农作物产量和生态环境造成极大的威胁, 林草植物对外界环境具有较强的
适应能力, 因此挖掘林草植物抗逆基因, 分析其抗逆机制已经成为当下的研究趋势 …